1s80
From Proteopedia
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| - | [[Image:1s80.gif|left|200px]] | + | [[Image:1s80.gif|left|200px]] |
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| - | '''Structure of Serine Acetyltranferase from Haemophilis influenzae Rd''' | + | {{Structure |
| + | |PDB= 1s80 |SIZE=350|CAPTION= <scene name='initialview01'>1s80</scene>, resolution 2.70Å | ||
| + | |SITE= | ||
| + | |LIGAND= | ||
| + | |ACTIVITY= [http://en.wikipedia.org/wiki/Serine_O-acetyltransferase Serine O-acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.30 2.3.1.30] | ||
| + | |GENE= CYSE, HI0606 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=727 Haemophilus influenzae]) | ||
| + | }} | ||
| + | |||
| + | '''Structure of Serine Acetyltranferase from Haemophilis influenzae Rd''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1S80 is a [ | + | 1S80 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S80 OCA]. |
==Reference== | ==Reference== | ||
| - | Structure of serine acetyltransferase from Haemophilus influenzae Rd., Gorman J, Shapiro L, Acta Crystallogr D Biol Crystallogr. 2004 Sep;60(Pt 9):1600-5. Epub 2004, Aug 26. PMID:[http:// | + | Structure of serine acetyltransferase from Haemophilus influenzae Rd., Gorman J, Shapiro L, Acta Crystallogr D Biol Crystallogr. 2004 Sep;60(Pt 9):1600-5. Epub 2004, Aug 26. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15333931 15333931] |
[[Category: Haemophilus influenzae]] | [[Category: Haemophilus influenzae]] | ||
[[Category: Serine O-acetyltransferase]] | [[Category: Serine O-acetyltransferase]] | ||
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[[Category: structural genomics; protein structure initiative; serine acetyltransferase; left-handed parallel beta-helix; nysgxrc]] | [[Category: structural genomics; protein structure initiative; serine acetyltransferase; left-handed parallel beta-helix; nysgxrc]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:01:42 2008'' |
Revision as of 12:01, 20 March 2008
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| , resolution 2.70Å | |||||||
|---|---|---|---|---|---|---|---|
| Gene: | CYSE, HI0606 (Haemophilus influenzae) | ||||||
| Activity: | Serine O-acetyltransferase, with EC number 2.3.1.30 | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Structure of Serine Acetyltranferase from Haemophilis influenzae Rd
Overview
The crystal structure of serine acetyltransferase (SAT) from Haemophilus influenzae Rd determined at 2.7 A resolution is presented. SAT is a member of a family of hexapeptide-containing transferases that contain six-residue tandem repeats (LIV)-G-X(4) that have been shown to form left-handed parallel beta-helices. In the current structure, each protomer is comprised of two domains: an N-terminal alpha-helical domain and a C-terminal left-handed parallel beta-helix domain. Although other members of this protein family are known to form trimeric structures, SAT forms a dimer of trimers in which the trimer interface is mediated through interactions between both the beta-helix domains and N-terminal domains; these trimers dimerize through contacts in the N-terminal domain. All dimer-of-trimer interactions are mediated through amino acids within an N-terminal extension common only to a subset of SATs, suggesting that members of this subfamily may also adopt hexameric structures. Putative active sites are formed by crevices between adjacent protomers in a trimer. Thus, six independent active sites exist in the hexameric enzyme complex.
About this Structure
1S80 is a Single protein structure of sequence from Haemophilus influenzae. Full crystallographic information is available from OCA.
Reference
Structure of serine acetyltransferase from Haemophilus influenzae Rd., Gorman J, Shapiro L, Acta Crystallogr D Biol Crystallogr. 2004 Sep;60(Pt 9):1600-5. Epub 2004, Aug 26. PMID:15333931
Page seeded by OCA on Thu Mar 20 14:01:42 2008
Categories: Haemophilus influenzae | Serine O-acetyltransferase | Single protein | Burley, S K. | Gogos, A. | Gorman, J. | NYSGXRC, New York Structural GenomiX Research Consortium. | Shapiro, L. | New york structural genomix research consortium | Nysgxrc | Psi | Structural genomics; protein structure initiative; serine acetyltransferase; left-handed parallel beta-helix; nysgxrc
