4iwx

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{{STRUCTURE_4iwx| PDB=4iwx | SCENE= }}
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==Rimk structure at 2.85A==
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===Rimk structure at 2.85A===
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<StructureSection load='4iwx' size='340' side='right' caption='[[4iwx]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
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{{ABSTRACT_PUBMED_23609986}}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4iwx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IWX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4IWX FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4iwy|4iwy]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">b0852, JW0836, rimK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 Escherichia coli K-12])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4iwx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4iwx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4iwx RCSB], [http://www.ebi.ac.uk/pdbsum/4iwx PDBsum]</span></td></tr>
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</table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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We report herein the crystal structure of E. coli RimK at 2.85 A resolution, an enzyme that catalyzes the post-translational addition of up to fifteen C-terminal glutamate residues to ribosomal protein S6. The structure belongs to the ATP-grasp superfamily and is organized as a tetramer, consistent with gel filtration analysis. Each subunit consists of three distinct structural domains and the active site is located in the cleft between these domains. The catalytic reaction appears to occur at the junction between the three domains since ATP binds between the B and C domains, and other substrates bind nearby. (c) Proteins 2013;. (c) 2013 Wiley Periodicals, Inc.
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==Function==
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Structure and function of Escherichia coli RimK, an ATP-grasp fold, L-glutamyl ligase enzyme.,Zhao G, Jin Z, Wang Y, Allewell NM, Tuchman M, Shi D Proteins. 2013 Apr 23. doi: 10.1002/prot.24311. PMID:23609986<ref>PMID:23609986</ref>
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[[http://www.uniprot.org/uniprot/RIMK_ECOLI RIMK_ECOLI]] Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6.
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==About this Structure==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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[[4iwx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IWX OCA].
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</div>
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:023609986</ref><references group="xtra"/><references/>
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__TOC__
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</StructureSection>
[[Category: Escherichia coli k-12]]
[[Category: Escherichia coli k-12]]
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[[Category: Allewell, N M.]]
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[[Category: Allewell, N M]]
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[[Category: Jin, Z.]]
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[[Category: Jin, Z]]
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[[Category: Shi, D.]]
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[[Category: Shi, D]]
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[[Category: Tuchman, M.]]
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[[Category: Tuchman, M]]
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[[Category: Zhao, G.]]
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[[Category: Zhao, G]]
[[Category: Atp-grasp fold]]
[[Category: Atp-grasp fold]]
[[Category: Ligase]]
[[Category: Ligase]]

Revision as of 13:11, 21 December 2014

Rimk structure at 2.85A

4iwx, resolution 2.85Å

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