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4k7z

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{{STRUCTURE_4k7z| PDB=4k7z | SCENE= }}
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==Crystal structure of the C136(42)A/C141(47)A double mutant of Tn501 MerA in complex with NADP and Hg2+==
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===Crystal structure of the C136(42)A/C141(47)A double mutant of Tn501 MerA in complex with NADP and Hg2+===
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<StructureSection load='4k7z' size='340' side='right' caption='[[4k7z]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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== Structural highlights ==
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==Function==
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<table><tr><td colspan='2'>[[4k7z]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K7Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4K7Z FirstGlance]. <br>
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[[http://www.uniprot.org/uniprot/MERA_PSEAI MERA_PSEAI]] Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1zk7|1zk7]], [[4k8d|4k8d]]</td></tr>
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==About this Structure==
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">merA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 Pseudomonas aeruginosa])</td></tr>
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[[4k7z]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K7Z OCA].
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mercury(II)_reductase Mercury(II) reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.16.1.1 1.16.1.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k7z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k7z OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4k7z RCSB], [http://www.ebi.ac.uk/pdbsum/4k7z PDBsum]</span></td></tr>
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</table>
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__TOC__
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</StructureSection>
[[Category: Pseudomonas aeruginosa]]
[[Category: Pseudomonas aeruginosa]]
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[[Category: Dong, A.]]
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[[Category: Dong, A]]
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[[Category: Falkowaski, M.]]
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[[Category: Falkowaski, M]]
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[[Category: Malone, M.]]
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[[Category: Malone, M]]
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[[Category: Miller, S M.]]
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[[Category: Miller, S M]]
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[[Category: Pai, E F.]]
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[[Category: Pai, E F]]
[[Category: Flavoenzyme]]
[[Category: Flavoenzyme]]
[[Category: Mercuric ion complex]]
[[Category: Mercuric ion complex]]

Revision as of 14:44, 21 December 2014

Crystal structure of the C136(42)A/C141(47)A double mutant of Tn501 MerA in complex with NADP and Hg2+

4k7z, resolution 1.50Å

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