4lg6

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{{STRUCTURE_4lg6| PDB=4lg6 | SCENE= }}
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==Crystal structure of ANKRA2-CCDC8 complex==
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===Crystal structure of ANKRA2-CCDC8 complex===
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<StructureSection load='4lg6' size='340' side='right' caption='[[4lg6]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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== Structural highlights ==
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==Disease==
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<table><tr><td colspan='2'>[[4lg6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LG6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LG6 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ANKRA2, ANKRA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lg6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lg6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4lg6 RCSB], [http://www.ebi.ac.uk/pdbsum/4lg6 PDBsum]</span></td></tr>
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</table>
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== Disease ==
[[http://www.uniprot.org/uniprot/CCDC8_HUMAN CCDC8_HUMAN]] 3M syndrome. The disease is caused by mutations affecting the gene represented in this entry.
[[http://www.uniprot.org/uniprot/CCDC8_HUMAN CCDC8_HUMAN]] 3M syndrome. The disease is caused by mutations affecting the gene represented in this entry.
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== Function ==
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==Function==
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[[http://www.uniprot.org/uniprot/ANRA2_HUMAN ANRA2_HUMAN]] May facilitate endocytosis by linking megalin to components of the cytoskeleton or endocytic machinery.
[[http://www.uniprot.org/uniprot/ANRA2_HUMAN ANRA2_HUMAN]] May facilitate endocytosis by linking megalin to components of the cytoskeleton or endocytic machinery.
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__TOC__
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==About this Structure==
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</StructureSection>
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[[4lg6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LG6 OCA].
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Arrowsmith, C H]]
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[[Category: Bian, C.]]
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[[Category: Bian, C]]
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[[Category: Bountra, C.]]
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[[Category: Bountra, C]]
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[[Category: Edwards, A M.]]
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[[Category: Edwards, A M]]
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[[Category: Mackenzie, F.]]
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[[Category: Mackenzie, F]]
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[[Category: Min, J.]]
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[[Category: Min, J]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Structural genomic]]
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[[Category: Tempel, W.]]
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[[Category: Tempel, W]]
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[[Category: Xu, C.]]
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[[Category: Xu, C]]
[[Category: Ankyrin repeat]]
[[Category: Ankyrin repeat]]
[[Category: Sgc]]
[[Category: Sgc]]
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[[Category: Structural genomics consortium]]
 
[[Category: Structural protein]]
[[Category: Structural protein]]

Revision as of 15:29, 21 December 2014

Crystal structure of ANKRA2-CCDC8 complex

4lg6, resolution 1.80Å

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