4l0r
From Proteopedia
(Difference between revisions)
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| - | + | ==Crystal structure of FGF2-interacting protein from Homo sapiens. Northeast Structural Genomics Consortium Target HR9027A.== | |
| - | + | <StructureSection load='4l0r' size='340' side='right' caption='[[4l0r]], [[Resolution|resolution]] 2.49Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | ==Disease== | + | <table><tr><td colspan='2'>[[4l0r]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L0R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4L0R FirstGlance]. <br> |
| + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CEP57, KIAA0092, TSP57 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4l0r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l0r OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4l0r RCSB], [http://www.ebi.ac.uk/pdbsum/4l0r PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
[[http://www.uniprot.org/uniprot/CEP57_HUMAN CEP57_HUMAN]] Mosaic variegated aneuploidy syndrome. The disease is caused by mutations affecting the gene represented in this entry. | [[http://www.uniprot.org/uniprot/CEP57_HUMAN CEP57_HUMAN]] Mosaic variegated aneuploidy syndrome. The disease is caused by mutations affecting the gene represented in this entry. | ||
| - | + | == Function == | |
| - | ==Function== | + | |
[[http://www.uniprot.org/uniprot/CEP57_HUMAN CEP57_HUMAN]] Centrosomal protein which may be required for microtubule attachment to centrosomes. May act by forming ring-like structures around microtubules. Mediates nuclear translocation and mitogenic activity of the internalized growth factor FGF2, but that of FGF1.<ref>PMID:22321063</ref> | [[http://www.uniprot.org/uniprot/CEP57_HUMAN CEP57_HUMAN]] Centrosomal protein which may be required for microtubule attachment to centrosomes. May act by forming ring-like structures around microtubules. Mediates nuclear translocation and mitogenic activity of the internalized growth factor FGF2, but that of FGF1.<ref>PMID:22321063</ref> | ||
| - | + | == References == | |
| - | == | + | <references/> |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | ||
| - | <references | + | |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Acton, T B | + | [[Category: Acton, T B]] |
| - | [[Category: Ciccosanti, C | + | [[Category: Ciccosanti, C]] |
| - | [[Category: Everett, J K | + | [[Category: Everett, J K]] |
| - | [[Category: Hunt, J F | + | [[Category: Hunt, J F]] |
| - | [[Category: Lew, S | + | [[Category: Lew, S]] |
| - | [[Category: Montelione, G T | + | [[Category: Montelione, G T]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Sahdev, S | + | [[Category: Sahdev, S]] |
| - | [[Category: Seetharaman, J | + | [[Category: Seetharaman, J]] |
| - | [[Category: Su, M | + | [[Category: Su, M]] |
| - | [[Category: Tong, L | + | [[Category: Tong, L]] |
| - | [[Category: Xiao, R | + | [[Category: Xiao, R]] |
[[Category: Cell cycle]] | [[Category: Cell cycle]] | ||
[[Category: Centrosomal protein]] | [[Category: Centrosomal protein]] | ||
[[Category: Cep57]] | [[Category: Cep57]] | ||
[[Category: Nesg]] | [[Category: Nesg]] | ||
| - | [[Category: Northeast structural genomics consortium]] | ||
[[Category: Psi-biology]] | [[Category: Psi-biology]] | ||
| - | [[Category: Structural genomic]] | ||
Revision as of 15:33, 21 December 2014
Crystal structure of FGF2-interacting protein from Homo sapiens. Northeast Structural Genomics Consortium Target HR9027A.
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Categories: Homo sapiens | Acton, T B | Ciccosanti, C | Everett, J K | Hunt, J F | Lew, S | Montelione, G T | Structural genomic | Sahdev, S | Seetharaman, J | Su, M | Tong, L | Xiao, R | Cell cycle | Centrosomal protein | Cep57 | Nesg | Psi-biology
