This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4kfg

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
{{STRUCTURE_4kfg| PDB=4kfg | SCENE= }}
+
==The DNA Gyrase B ATP binding domain of Escherichia coli in complex with a small molecule inhibitor.==
-
===The DNA Gyrase B ATP binding domain of Escherichia coli in complex with a small molecule inhibitor.===
+
<StructureSection load='4kfg' size='340' side='right' caption='[[4kfg]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[4kfg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KFG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KFG FirstGlance]. <br>
 +
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DOO:6-FLUORO-4-[(3AR,6AR)-HEXAHYDROPYRROLO[3,4-B]PYRROL-5(1H)-YL]-N-METHYL-2-[(2-METHYLPYRIMIDIN-5-YL)OXY]-9H-PYRIMIDO[4,5-B]INDOL-8-AMINE'>DOO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
 +
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4k4o|4k4o]]</td></tr>
 +
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">acrB, himB, hisU, nalC, parA, pcbA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
 +
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_topoisomerase_(ATP-hydrolyzing) DNA topoisomerase (ATP-hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.3 5.99.1.3] </span></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kfg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kfg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kfg RCSB], [http://www.ebi.ac.uk/pdbsum/4kfg PDBsum]</span></td></tr>
 +
</table>
-
==Function==
+
==See Also==
-
[[http://www.uniprot.org/uniprot/GYRB_ECOLI GYRB_ECOLI]] DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings.<ref>PMID:12051843</ref> <ref>PMID:18642932</ref> <ref>PMID:20675723</ref>
+
*[[Gyrase|Gyrase]]
-
 
+
__TOC__
-
==About this Structure==
+
</StructureSection>
-
[[4kfg]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KFG OCA].
+
[[Category: Ecoli]]
-
 
+
[[Category: Akers-Rodriguez, S]]
-
==Reference==
+
[[Category: Bensen, D C]]
-
<references group="xtra"/><references/>
+
[[Category: Lam, T]]
-
[[Category: Akers-Rodriguez, S.]]
+
[[Category: Tari, L W]]
-
[[Category: Bensen, D C.]]
+
-
[[Category: Lam, T.]]
+
-
[[Category: Tari, L W.]]
+
[[Category: Atp-binding]]
[[Category: Atp-binding]]
[[Category: Atp-binding domain]]
[[Category: Atp-binding domain]]

Revision as of 16:23, 21 December 2014

The DNA Gyrase B ATP binding domain of Escherichia coli in complex with a small molecule inhibitor.

4kfg, resolution 1.60Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools