1sp3

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[[Image:1sp3.jpg|left|200px]]<br /><applet load="1sp3" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1sp3.jpg|left|200px]]
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caption="1sp3, resolution 2.20&Aring;" />
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'''Crystal structure of octaheme cytochrome c from Shewanella oneidensis'''<br />
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{{Structure
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|PDB= 1sp3 |SIZE=350|CAPTION= <scene name='initialview01'>1sp3</scene>, resolution 2.20&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene> and <scene name='pdbligand=HEM:PROTOPORPHYRIN IX CONTAINING FE'>HEM</scene>
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|ACTIVITY=
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|GENE= SO4144 (tigr locus) ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2 Bacteria])
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}}
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'''Crystal structure of octaheme cytochrome c from Shewanella oneidensis'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1SP3 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bacteria Bacteria] with <scene name='pdbligand=SCN:'>SCN</scene> and <scene name='pdbligand=HEM:'>HEM</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SP3 OCA].
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1SP3 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacteria Bacteria]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SP3 OCA].
==Reference==
==Reference==
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Octaheme tetrathionate reductase is a respiratory enzyme with novel heme ligation., Mowat CG, Rothery E, Miles CS, McIver L, Doherty MK, Drewette K, Taylor P, Walkinshaw MD, Chapman SK, Reid GA, Nat Struct Mol Biol. 2004 Oct;11(10):1023-4. Epub 2004 Sep 7. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15361860 15361860]
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Octaheme tetrathionate reductase is a respiratory enzyme with novel heme ligation., Mowat CG, Rothery E, Miles CS, McIver L, Doherty MK, Drewette K, Taylor P, Walkinshaw MD, Chapman SK, Reid GA, Nat Struct Mol Biol. 2004 Oct;11(10):1023-4. Epub 2004 Sep 7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15361860 15361860]
[[Category: Bacteria]]
[[Category: Bacteria]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: octaheme]]
[[Category: octaheme]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:03:46 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:07:55 2008''

Revision as of 12:07, 20 March 2008

Image:1sp3.jpg


PDB ID 1sp3

Drag the structure with the mouse to rotate
, resolution 2.20Å
Ligands: and
Gene: SO4144 (tigr locus) (Bacteria)
Coordinates: save as pdb, mmCIF, xml



Crystal structure of octaheme cytochrome c from Shewanella oneidensis


Overview

We have isolated a soluble cytochrome from Shewanella oneidensis that contains eight covalently attached heme groups and determined its crystal structure. One of these hemes exhibits novel ligation of the iron atom by the epsilon-amino group of a lysine residue, despite its attachment via a typical CXXCH motif. This heme is most likely the active site for tetrathionate reduction, a reaction catalyzed efficiently by this enzyme.

About this Structure

1SP3 is a Single protein structure of sequence from Bacteria. Full crystallographic information is available from OCA.

Reference

Octaheme tetrathionate reductase is a respiratory enzyme with novel heme ligation., Mowat CG, Rothery E, Miles CS, McIver L, Doherty MK, Drewette K, Taylor P, Walkinshaw MD, Chapman SK, Reid GA, Nat Struct Mol Biol. 2004 Oct;11(10):1023-4. Epub 2004 Sep 7. PMID:15361860

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