4kzm

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{{STRUCTURE_4kzm| PDB=4kzm | SCENE= }}
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==Crystal Structure of TR3 LBD S553A Mutant==
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===Crystal Structure of TR3 LBD S553A Mutant===
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<StructureSection load='4kzm' size='340' side='right' caption='[[4kzm]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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== Structural highlights ==
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==Function==
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<table><tr><td colspan='2'>[[4kzm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KZM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KZM FirstGlance]. <br>
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[[http://www.uniprot.org/uniprot/NR4A1_HUMAN NR4A1_HUMAN]] Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2.<ref>PMID:15466594</ref>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4kzi|4kzi]], [[4kzj|4kzj]], [[4jgv|4jgv]]</td></tr>
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==About this Structure==
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GFRP1, HMR, NAK1, NR4A1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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[[4kzm]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KZM OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kzm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kzm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kzm RCSB], [http://www.ebi.ac.uk/pdbsum/4kzm PDBsum]</span></td></tr>
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</table>
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==Reference==
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__TOC__
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<references group="xtra"/><references/>
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</StructureSection>
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[[Category: Cai, Q.]]
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[[Category: Human]]
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[[Category: Chen, H.]]
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[[Category: Cai, Q]]
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[[Category: Li, A.]]
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[[Category: Chen, H]]
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[[Category: Li, F.]]
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[[Category: Li, A]]
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[[Category: Lin, T.]]
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[[Category: Li, F]]
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[[Category: Tian, X.]]
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[[Category: Lin, T]]
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[[Category: Wang, W.]]
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[[Category: Tian, X]]
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[[Category: Wang, Y.]]
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[[Category: Wang, W]]
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[[Category: Wu, Q.]]
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[[Category: Wang, Y]]
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[[Category: Xing, Y.]]
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[[Category: Wu, Q]]
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[[Category: Zhang, Q.]]
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[[Category: Xing, Y]]
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[[Category: Zhang, Q]]
[[Category: Orphan nuclear receptor]]
[[Category: Orphan nuclear receptor]]
[[Category: Transcription]]
[[Category: Transcription]]

Revision as of 17:10, 21 December 2014

Crystal Structure of TR3 LBD S553A Mutant

4kzm, resolution 2.30Å

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