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1st8
From Proteopedia
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| - | [[Image:1st8.gif|left|200px]] | + | [[Image:1st8.gif|left|200px]] |
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| - | '''Crystal structure of fructan 1-exohydrolase IIa from Cichorium intybus''' | + | {{Structure |
| + | |PDB= 1st8 |SIZE=350|CAPTION= <scene name='initialview01'>1st8</scene>, resolution 2.35Å | ||
| + | |SITE= | ||
| + | |LIGAND= <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene> | ||
| + | |ACTIVITY= [http://en.wikipedia.org/wiki/Fructan_beta-fructosidase Fructan beta-fructosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.80 3.2.1.80] | ||
| + | |GENE= 1-feh IIa ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=13427 Cichorium intybus]) | ||
| + | }} | ||
| + | |||
| + | '''Crystal structure of fructan 1-exohydrolase IIa from Cichorium intybus''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1ST8 is a [ | + | 1ST8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Cichorium_intybus Cichorium intybus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ST8 OCA]. |
==Reference== | ==Reference== | ||
| - | X-ray diffraction structure of a plant glycosyl hydrolase family 32 protein: fructan 1-exohydrolase IIa of Cichorium intybus., Verhaest M, Ende WV, Roy KL, De Ranter CJ, Laere AV, Rabijns A, Plant J. 2005 Feb;41(3):400-11. PMID:[http:// | + | X-ray diffraction structure of a plant glycosyl hydrolase family 32 protein: fructan 1-exohydrolase IIa of Cichorium intybus., Verhaest M, Ende WV, Roy KL, De Ranter CJ, Laere AV, Rabijns A, Plant J. 2005 Feb;41(3):400-11. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15659099 15659099] |
[[Category: Cichorium intybus]] | [[Category: Cichorium intybus]] | ||
[[Category: Fructan beta-fructosidase]] | [[Category: Fructan beta-fructosidase]] | ||
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[[Category: five fold beta propeller]] | [[Category: five fold beta propeller]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:09:20 2008'' |
Revision as of 12:09, 20 March 2008
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| , resolution 2.35Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | |||||||
| Gene: | 1-feh IIa (Cichorium intybus) | ||||||
| Activity: | Fructan beta-fructosidase, with EC number 3.2.1.80 | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal structure of fructan 1-exohydrolase IIa from Cichorium intybus
Overview
Fructan 1-exohydrolase, an enzyme involved in fructan degradation, belongs to the glycosyl hydrolase family 32. The structure of isoenzyme 1-FEH IIa from Cichorium intybus is described at a resolution of 2.35 A. The structure consists of an N-terminal fivefold beta-propeller domain connected to two C-terminal beta-sheets. The putative active site is located entirely in the beta-propeller domain and is formed by amino acids which are highly conserved within glycosyl hydrolase family 32. The fructan-binding site is thought to be in the cleft formed between the two domains. The 1-FEH IIa structure is compared with the structures of two homologous but functionally different enzymes: a levansucrase from Bacillus subtilis (glycosyl hydrolase family 68) and an invertase from Thermotoga maritima (glycosyl hydrolase family 32).
About this Structure
1ST8 is a Single protein structure of sequence from Cichorium intybus. Full crystallographic information is available from OCA.
Reference
X-ray diffraction structure of a plant glycosyl hydrolase family 32 protein: fructan 1-exohydrolase IIa of Cichorium intybus., Verhaest M, Ende WV, Roy KL, De Ranter CJ, Laere AV, Rabijns A, Plant J. 2005 Feb;41(3):400-11. PMID:15659099
Page seeded by OCA on Thu Mar 20 14:09:20 2008
