4co8

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{{STRUCTURE_4co8| PDB=4co8 | SCENE= }}
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==Structure of the DNA binding ETS domain of human ETV4==
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===Structure of the DNA binding ETS domain of human ETV4===
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<StructureSection load='4co8' size='340' side='right' caption='[[4co8]], [[Resolution|resolution]] 1.05&Aring;' scene=''>
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== Structural highlights ==
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==Disease==
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<table><tr><td colspan='2'>[[4co8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CO8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CO8 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4co8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4co8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4co8 RCSB], [http://www.ebi.ac.uk/pdbsum/4co8 PDBsum]</span></td></tr>
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</table>
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== Disease ==
[[http://www.uniprot.org/uniprot/ETV4_HUMAN ETV4_HUMAN]] Ewing sarcoma.
[[http://www.uniprot.org/uniprot/ETV4_HUMAN ETV4_HUMAN]] Ewing sarcoma.
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== Function ==
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==Function==
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[[http://www.uniprot.org/uniprot/ETV4_HUMAN ETV4_HUMAN]] Transcriptional activator that binds to the enhancer of the adenovirus E1A gene; the core-binding sequence is 5'[AC]GGA[AT]GT-3'.<ref>PMID:19307308</ref>
[[http://www.uniprot.org/uniprot/ETV4_HUMAN ETV4_HUMAN]] Transcriptional activator that binds to the enhancer of the adenovirus E1A gene; the core-binding sequence is 5'[AC]GGA[AT]GT-3'.<ref>PMID:19307308</ref>
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== References ==
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==About this Structure==
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<references/>
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[[4co8]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CO8 OCA].
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__TOC__
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</StructureSection>
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==Reference==
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[[Category: Human]]
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<references group="xtra"/><references/>
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[[Category: Arrowsmith, C H]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Bountra, C]]
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[[Category: Bountra, C.]]
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[[Category: Burgess-Brown, N]]
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[[Category: Burgess-Brown, N.]]
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[[Category: Cooper, C D.O]]
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[[Category: Cooper, C D.O.]]
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[[Category: Delft, F von]]
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[[Category: Delft, F von.]]
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[[Category: Edwards, A M]]
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[[Category: Edwards, A M.]]
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[[Category: Gileadi, O]]
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[[Category: Gileadi, O.]]
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[[Category: Kopec, J]]
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[[Category: Kopec, J.]]
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[[Category: Newman, J A]]
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[[Category: Newman, J A.]]
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[[Category: Shrestha, L]]
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[[Category: Shrestha, L.]]
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[[Category: Transcription]]
[[Category: Transcription]]

Revision as of 17:26, 21 December 2014

Structure of the DNA binding ETS domain of human ETV4

4co8, resolution 1.05Å

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