1swm

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[[Image:1swm.gif|left|200px]]<br /><applet load="1swm" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1swm.gif|left|200px]]
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caption="1swm, resolution 1.8&Aring;" />
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'''X-RAY CRYSTAL STRUCTURE OF THE FERRIC SPERM WHALE MYOGLOBIN: IMIDAZOLE COMPLEX AT 2.0 ANGSTROMS RESOLUTION'''<br />
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{{Structure
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|PDB= 1swm |SIZE=350|CAPTION= <scene name='initialview01'>1swm</scene>, resolution 1.8&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=AZI:AZIDE+ION'>AZI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=HEM:PROTOPORPHYRIN IX CONTAINING FE'>HEM</scene>
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|ACTIVITY=
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|GENE=
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}}
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'''X-RAY CRYSTAL STRUCTURE OF THE FERRIC SPERM WHALE MYOGLOBIN: IMIDAZOLE COMPLEX AT 2.0 ANGSTROMS RESOLUTION'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1SWM is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Physeter_catodon Physeter catodon] with <scene name='pdbligand=AZI:'>AZI</scene>, <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=HEM:'>HEM</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SWM OCA].
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1SWM is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Physeter_catodon Physeter catodon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SWM OCA].
==Reference==
==Reference==
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X-ray crystal structure of the ferric sperm whale myoglobin: imidazole complex at 2.0 A resolution., Lionetti C, Guanziroli MG, Frigerio F, Ascenzi P, Bolognesi M, J Mol Biol. 1991 Feb 5;217(3):409-12. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=1994031 1994031]
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X-ray crystal structure of the ferric sperm whale myoglobin: imidazole complex at 2.0 A resolution., Lionetti C, Guanziroli MG, Frigerio F, Ascenzi P, Bolognesi M, J Mol Biol. 1991 Feb 5;217(3):409-12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/1994031 1994031]
[[Category: Physeter catodon]]
[[Category: Physeter catodon]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: oxygen transport]]
[[Category: oxygen transport]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:06:05 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:10:39 2008''

Revision as of 12:10, 20 March 2008

Image:1swm.gif


PDB ID 1swm

Drag the structure with the mouse to rotate
, resolution 1.8Å
Ligands: , and
Coordinates: save as pdb, mmCIF, xml



X-RAY CRYSTAL STRUCTURE OF THE FERRIC SPERM WHALE MYOGLOBIN: IMIDAZOLE COMPLEX AT 2.0 ANGSTROMS RESOLUTION


Overview

The X-ray crystal structure of the ferric sperm whale (Physeter catodon) myoglobin:imidazole complex has been refined at 2.0 A resolution, to a final R-factor of 14.8%. The overall conformation of the protein is little affected by binding of the ligand. Imidazole is co-ordinated to the heme iron at the distal site, and forces distinguishable local changes in the surrounding protein residues. His64(E7) swings out of the distal pocket and becomes substantially exposed to the solvent: nevertheless, it stabilizes the exogenous ligand by hydrogen bonding. The side-chains of residues Arg45(CD3) and Asp60(E3) are also affected by imidazole association.

About this Structure

1SWM is a Single protein structure of sequence from Physeter catodon. Full crystallographic information is available from OCA.

Reference

X-ray crystal structure of the ferric sperm whale myoglobin: imidazole complex at 2.0 A resolution., Lionetti C, Guanziroli MG, Frigerio F, Ascenzi P, Bolognesi M, J Mol Biol. 1991 Feb 5;217(3):409-12. PMID:1994031

Page seeded by OCA on Thu Mar 20 14:10:39 2008

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