2xrf

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
{{STRUCTURE_2xrf| PDB=2xrf | SCENE= }}
+
==Crystal structure of human uridine phosphorylase 2==
-
===Crystal structure of human uridine phosphorylase 2===
+
<StructureSection load='2xrf' size='340' side='right' caption='[[2xrf]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
-
 
+
== Structural highlights ==
-
==Function==
+
<table><tr><td colspan='2'>[[2xrf]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XRF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XRF FirstGlance]. <br>
-
[[http://www.uniprot.org/uniprot/UPP2_HUMAN UPP2_HUMAN]] Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates.
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=URA:URACIL'>URA</scene></td></tr>
-
 
+
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Uridine_phosphorylase Uridine phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.3 2.4.2.3] </span></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xrf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xrf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xrf RCSB], [http://www.ebi.ac.uk/pdbsum/2xrf PDBsum]</span></td></tr>
-
[[2xrf]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XRF OCA].
+
</table>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xr/2xrf_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
 +
<div style="clear:both"></div>
==See Also==
==See Also==
*[[Myosin|Myosin]]
*[[Myosin|Myosin]]
 +
*[[Uridine phosphorylase|Uridine phosphorylase]]
 +
__TOC__
 +
</StructureSection>
[[Category: Human]]
[[Category: Human]]
[[Category: Uridine phosphorylase]]
[[Category: Uridine phosphorylase]]
-
[[Category: Arrowsmith, C H.]]
+
[[Category: Arrowsmith, C H]]
-
[[Category: Berg, S Van Der.]]
+
[[Category: Berg, S Van Der]]
-
[[Category: Berglund, H.]]
+
[[Category: Berglund, H]]
-
[[Category: Bountra, C.]]
+
[[Category: Bountra, C]]
-
[[Category: Collins, R.]]
+
[[Category: Collins, R]]
-
[[Category: Edwards, A M.]]
+
[[Category: Edwards, A M]]
-
[[Category: Flodin, S.]]
+
[[Category: Flodin, S]]
-
[[Category: Flores, A.]]
+
[[Category: Flores, A]]
-
[[Category: Graslund, S.]]
+
[[Category: Graslund, S]]
-
[[Category: Hammarstrom, M.]]
+
[[Category: Hammarstrom, M]]
-
[[Category: Johansson, I.]]
+
[[Category: Johansson, I]]
-
[[Category: Karlberg, T.]]
+
[[Category: Karlberg, T]]
-
[[Category: Kol, S.]]
+
[[Category: Kol, S]]
-
[[Category: Kotenyova, T.]]
+
[[Category: Kotenyova, T]]
-
[[Category: Kouznetsova, E.]]
+
[[Category: Kouznetsova, E]]
-
[[Category: Moche, M.]]
+
[[Category: Moche, M]]
-
[[Category: Nordlund, P.]]
+
[[Category: Nordlund, P]]
-
[[Category: Nyman, T.]]
+
[[Category: Nyman, T]]
-
[[Category: Persson, C.]]
+
[[Category: Persson, C]]
-
[[Category: Schuler, H.]]
+
[[Category: Schuler, H]]
-
[[Category: Schutz, P.]]
+
[[Category: Schutz, P]]
-
[[Category: Siponen, M I.]]
+
[[Category: Siponen, M I]]
-
[[Category: Thorsell, A G.]]
+
[[Category: Thorsell, A G]]
-
[[Category: Tresaugues, L.]]
+
[[Category: Tresaugues, L]]
-
[[Category: Wahlberg, E.]]
+
[[Category: Wahlberg, E]]
-
[[Category: Weigelt, J.]]
+
[[Category: Weigelt, J]]
-
[[Category: Welin, M.]]
+
[[Category: Welin, M]]
[[Category: Transferase]]
[[Category: Transferase]]

Revision as of 17:59, 21 December 2014

Crystal structure of human uridine phosphorylase 2

2xrf, resolution 2.30Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2xrf"
Personal tools