4l5f

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{{STRUCTURE_4l5f| PDB=4l5f | SCENE= }}
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==Crystal Structure of DENV1-E106 Fab bound to DENV-1 Envelope protein DIII==
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===Crystal Structure of DENV1-E106 Fab bound to DENV-1 Envelope protein DIII===
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<StructureSection load='4l5f' size='340' side='right' caption='[[4l5f]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4l5f]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Dengue_virus_1 Dengue virus 1] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L5F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4L5F FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">E ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11053 Dengue virus 1])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4l5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l5f OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4l5f RCSB], [http://www.ebi.ac.uk/pdbsum/4l5f PDBsum]</span></td></tr>
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</table>
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==Function==
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==See Also==
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[[http://www.uniprot.org/uniprot/Q8BE40_9FLAV Q8BE40_9FLAV]] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS026470_004_099774]
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*[[Monoclonal Antibody|Monoclonal Antibody]]
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__TOC__
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==About this Structure==
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</StructureSection>
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[[4l5f]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L5F OCA].
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[[Category: Dengue virus 1]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
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[[Category: Structural genomic]]
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[[Category: Edeling, M A.]]
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[[Category: Edeling, M A]]
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[[Category: Fremont, D H.]]
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[[Category: Fremont, D H]]
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[[Category: Nelson, C A.]]
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[[Category: Nelson, C A]]
[[Category: Antibody]]
[[Category: Antibody]]
[[Category: Antibody epitope]]
[[Category: Antibody epitope]]

Revision as of 18:12, 21 December 2014

Crystal Structure of DENV1-E106 Fab bound to DENV-1 Envelope protein DIII

4l5f, resolution 2.45Å

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