2m2a

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{{STRUCTURE_2m2a| PDB=2m2a | SCENE= }}
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==NMR solution structure of the two domain PPIase SlpA from Escherichia coli==
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===NMR solution structure of the two domain PPIase SlpA from Escherichia coli===
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<StructureSection load='2m2a' size='340' side='right' caption='[[2m2a]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
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== Structural highlights ==
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==Function==
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<table><tr><td colspan='2'>[[2m2a]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M2A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2M2A FirstGlance]. <br>
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[[http://www.uniprot.org/uniprot/FKBX_ECOLI FKBX_ECOLI]] PPIases accelerate the folding of proteins. Substrate specificity investigated with 'Suc-Ala-Xaa-Pro-Phe-4-nitroanilide' where Xaa is the amino acid tested, was found to be Phe > Leu >> Ile > Lys = Ala > Trp > His >> Gln.
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</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidylprolyl_isomerase Peptidylprolyl isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.2.1.8 5.2.1.8] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2m2a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m2a OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2m2a RCSB], [http://www.ebi.ac.uk/pdbsum/2m2a PDBsum]</span></td></tr>
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==About this Structure==
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</table>
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[[2m2a]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M2A OCA].
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__TOC__
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Peptidylprolyl isomerase]]
[[Category: Peptidylprolyl isomerase]]
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[[Category: Balbach, J.]]
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[[Category: Balbach, J]]
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[[Category: Kovermann, M.]]
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[[Category: Kovermann, M]]
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[[Category: Weininger, U.]]
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[[Category: Weininger, U]]
[[Category: Fkbp fold]]
[[Category: Fkbp fold]]
[[Category: Isomerase]]
[[Category: Isomerase]]

Revision as of 18:15, 21 December 2014

NMR solution structure of the two domain PPIase SlpA from Escherichia coli

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