1szj

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[[Image:1szj.gif|left|200px]]<br /><applet load="1szj" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1szj.gif|left|200px]]
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caption="1szj, resolution 2.0&Aring;" />
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'''STRUCTURE OF HOLO-GLYCERALDEHYDE-3-PHOSPHATE-DEHYDROGENASE FROM PALINURUS VERSICOLOR REFINED 2.0 ANGSTROM RESOLUTION'''<br />
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{{Structure
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|PDB= 1szj |SIZE=350|CAPTION= <scene name='initialview01'>1szj</scene>, resolution 2.0&Aring;
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|SITE= <scene name='pdbsite=ACT:Active+Site+Residues+CYS+149+And+HIS+176'>ACT</scene>
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|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Glyceraldehyde-3-phosphate_dehydrogenase_(phosphorylating) Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.12 1.2.1.12]
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|GENE=
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}}
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'''STRUCTURE OF HOLO-GLYCERALDEHYDE-3-PHOSPHATE-DEHYDROGENASE FROM PALINURUS VERSICOLOR REFINED 2.0 ANGSTROM RESOLUTION'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1SZJ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Palinurus_versicolor Palinurus versicolor] with <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=NAD:'>NAD</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Glyceraldehyde-3-phosphate_dehydrogenase_(phosphorylating) Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.12 1.2.1.12] Known structural/functional Site: <scene name='pdbsite=ACT:Active+Site+Residues+CYS+149+And+HIS+176'>ACT</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SZJ OCA].
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1SZJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Palinurus_versicolor Palinurus versicolor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SZJ OCA].
==Reference==
==Reference==
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Preliminary crystallographic studies of lobster D-glyceraldehyde-3-phosphate dehydrogenase and the modified enzyme carrying the fluorescent derivative., Song SY, Gao YG, Zhou JM, Tsou CL, J Mol Biol. 1983 Dec 5;171(2):225-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=6655693 6655693]
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Preliminary crystallographic studies of lobster D-glyceraldehyde-3-phosphate dehydrogenase and the modified enzyme carrying the fluorescent derivative., Song SY, Gao YG, Zhou JM, Tsou CL, J Mol Biol. 1983 Dec 5;171(2):225-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/6655693 6655693]
[[Category: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)]]
[[Category: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)]]
[[Category: Palinurus versicolor]]
[[Category: Palinurus versicolor]]
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[[Category: oxidoreductase]]
[[Category: oxidoreductase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:07:52 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:11:38 2008''

Revision as of 12:11, 20 March 2008


PDB ID 1szj

Drag the structure with the mouse to rotate
, resolution 2.0Å
Sites:
Ligands: and
Activity: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating), with EC number 1.2.1.12
Coordinates: save as pdb, mmCIF, xml



STRUCTURE OF HOLO-GLYCERALDEHYDE-3-PHOSPHATE-DEHYDROGENASE FROM PALINURUS VERSICOLOR REFINED 2.0 ANGSTROM RESOLUTION


Overview

When the active-site carboxymethylated D-glyceraldehyde-3-phosphate dehydrogenase is irradiated with ultraviolet light in the presence of NAD+, a fluorescent NAD derivative that is covalently linked to the enzyme is obtained. A preliminary crystallographic study of this fluorescent derivative, as well as of the native and the carboxymethylated enzymes from Palinurus versicolor, showed that they are isomorphous and belong to space group C2 as reported for the native enzyme from Palinurus vulgaris. The three forms of the enzyme, although they have identical unit cell parameters, differ considerably in their diffraction patterns, indicating marked differences in conformation in spite of the fact that they differ chemically only in a restricted region around the active site.

About this Structure

1SZJ is a Single protein structure of sequence from Palinurus versicolor. Full crystallographic information is available from OCA.

Reference

Preliminary crystallographic studies of lobster D-glyceraldehyde-3-phosphate dehydrogenase and the modified enzyme carrying the fluorescent derivative., Song SY, Gao YG, Zhou JM, Tsou CL, J Mol Biol. 1983 Dec 5;171(2):225-8. PMID:6655693

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