1p1y
From Proteopedia
(Difference between revisions)
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| - | + | ==Crystal structure of a continuous three-dimensional DNA lattice from d(GGACAGATGGGAG)== | |
| - | + | <StructureSection load='1p1y' size='340' side='right' caption='[[1p1y]], [[Resolution|resolution]] 2.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| + | <table><tr><td colspan='2'>[[1p1y]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P1Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1P1Y FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
| + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=BRU:5-BROMO-2-DEOXYURIDINE-5-MONOPHOSPHATE'>BRU</scene>, <scene name='pdbligand=CBR:5-BROMO-2-DEOXY-CYTIDINE-5-MONOPHOSPHATE'>CBR</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1p1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p1y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1p1y RCSB], [http://www.ebi.ac.uk/pdbsum/1p1y PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | DNA has proved to be a versatile material for the rational design and assembly of nanometer scale objects. Here we report the crystal structure of a continuous three-dimensional DNA lattice formed by the self-assembly of a DNA 13-mer. The structure consists of stacked layers of parallel helices with adjacent layers linked through parallel-stranded base pairing. The hexagonal lattice geometry contains solvent channels that appear large enough to allow 3'-linked guest molecules into the crystal. We have successfully used these parallel base pairs to design and produce crystals with greatly enlarged solvent channels. This lattice may have applications as a molecular scaffold for structure determination of guest molecules, as a molecular sieve, or in the assembly of molecular electronics. Predictable non-Watson-Crick base pairs, like those described here, may present a new tool in structural DNA nanotechnology. | ||
| - | + | Crystal structure of a continuous three-dimensional DNA lattice.,Paukstelis PJ, Nowakowski J, Birktoft JJ, Seeman NC Chem Biol. 2004 Aug;11(8):1119-26. PMID:15324813<ref>PMID:15324813</ref> | |
| - | + | ||
| - | == | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
| - | + | </div> | |
| - | [[Category: Birktoft, J J | + | == References == |
| - | [[Category: Nowakowski, J | + | <references/> |
| - | [[Category: Paukstelis, P J | + | __TOC__ |
| - | [[Category: Seeman, N C | + | </StructureSection> |
| + | [[Category: Birktoft, J J]] | ||
| + | [[Category: Nowakowski, J]] | ||
| + | [[Category: Paukstelis, P J]] | ||
| + | [[Category: Seeman, N C]] | ||
[[Category: Continuous three-dimensional dna lattice]] | [[Category: Continuous three-dimensional dna lattice]] | ||
[[Category: Dna]] | [[Category: Dna]] | ||
[[Category: Parallel-stranded base pair]] | [[Category: Parallel-stranded base pair]] | ||
Revision as of 05:03, 22 December 2014
Crystal structure of a continuous three-dimensional DNA lattice from d(GGACAGATGGGAG)
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