1pup
From Proteopedia
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| - | + | ==CRYSTAL STRUCTURE OF A PEPTIDE NUCLEIC ACID (PNA) DUPLEX AT 1.7 ANGSTROMS RESOLUTION== | |
| - | + | <StructureSection load='1pup' size='340' side='right' caption='[[1pup]], [[Resolution|resolution]] 1.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| + | <table><tr><td colspan='2'>[[1pup]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PUP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1PUP FirstGlance]. <br> | ||
| + | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=APN:2-AMINOETHYLGLYCINE-CARBONYLMETHYLENE-ADENINE'>APN</scene>, <scene name='pdbligand=CPN:2-AMINOETHYLGLYCINE-CARBONYLMETHYLENE-CYTOSINE'>CPN</scene>, <scene name='pdbligand=GPN:2-AMINOETHYLGLYCINE-CARBONYLMETHYLENE-GUANINE'>GPN</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene>, <scene name='pdbligand=TPN:2-AMINOETHYLGLYCINE-CARBONYLMETHYLENE-THYMINE'>TPN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1pup FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pup OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1pup RCSB], [http://www.ebi.ac.uk/pdbsum/1pup PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The crystal structure of a PNA duplex reveals both a right- and a left-handed helix in the unit cell. The helices are wide (28A), large pitched (18bp) with the base pairs perpendicular to the helix axis, thereby demonstrating that PNA besides adapting to oligonucleotide partners also has a unique structure by itself. | ||
| - | + | Crystal structure of a peptide nucleic acid (PNA) duplex at 1.7 A resolution.,Rasmussen H, Kastrup JS, Nielsen JN, Nielsen JM, Nielsen PE Nat Struct Biol. 1997 Feb;4(2):98-101. PMID:9033585<ref>PMID:9033585</ref> | |
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| - | == | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
| - | + | </div> | |
| - | [[Category: Kastrup, J S | + | == References == |
| - | [[Category: Rasmussen, H | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Kastrup, J S]] | ||
| + | [[Category: Rasmussen, H]] | ||
[[Category: Dna analogue]] | [[Category: Dna analogue]] | ||
[[Category: Double helix]] | [[Category: Double helix]] | ||
[[Category: Peptide nucleic acid]] | [[Category: Peptide nucleic acid]] | ||
Revision as of 05:21, 22 December 2014
CRYSTAL STRUCTURE OF A PEPTIDE NUCLEIC ACID (PNA) DUPLEX AT 1.7 ANGSTROMS RESOLUTION
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