2lly

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<StructureSection load='2lly' size='340' side='right' caption='[[2lly]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2lly' size='340' side='right' caption='[[2lly]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2lly]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LLY OCA]. <br>
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<table><tr><td colspan='2'>[[2lly]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LLY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LLY FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2lm2|2lm2]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2lm2|2lm2]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CHRNA4, NACRA4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CHRNA4, NACRA4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lly FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lly OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lly RCSB], [http://www.ebi.ac.uk/pdbsum/2lly PDBsum]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lly FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lly OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lly RCSB], [http://www.ebi.ac.uk/pdbsum/2lly PDBsum]</span></td></tr>
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</table>
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<table>
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== Disease ==
== Disease ==
[[http://www.uniprot.org/uniprot/ACHA4_HUMAN ACHA4_HUMAN]] Autosomal dominant nocturnal frontal lobe epilepsy. The disease is caused by mutations affecting the gene represented in this entry.
[[http://www.uniprot.org/uniprot/ACHA4_HUMAN ACHA4_HUMAN]] Autosomal dominant nocturnal frontal lobe epilepsy. The disease is caused by mutations affecting the gene represented in this entry.
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NMR structures of the transmembrane domains of the alpha4beta2 nAChR.,Bondarenko V, Mowrey D, Tillman T, Cui T, Liu LT, Xu Y, Tang P Biochim Biophys Acta. 2012 Feb 14;1818(5):1261-1268. PMID:22361591<ref>PMID:22361591</ref>
NMR structures of the transmembrane domains of the alpha4beta2 nAChR.,Bondarenko V, Mowrey D, Tillman T, Cui T, Liu LT, Xu Y, Tang P Biochim Biophys Acta. 2012 Feb 14;1818(5):1261-1268. PMID:22361591<ref>PMID:22361591</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
== References ==
== References ==
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Bondarenko, V.]]
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[[Category: Bondarenko, V]]
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[[Category: Cui, T.]]
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[[Category: Cui, T]]
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[[Category: Liu, L T.]]
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[[Category: Liu, L T]]
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[[Category: Mowrey, D.]]
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[[Category: Mowrey, D]]
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[[Category: Tang, P.]]
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[[Category: Tang, P]]
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[[Category: Tillman, T.]]
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[[Category: Tillman, T]]
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[[Category: Xu, Y.]]
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[[Category: Xu, Y]]
[[Category: Acetylcholine receptor]]
[[Category: Acetylcholine receptor]]
[[Category: Transmembrane domain]]
[[Category: Transmembrane domain]]
[[Category: Transport protein]]
[[Category: Transport protein]]

Revision as of 05:44, 22 December 2014

NMR structures of the transmembrane domains of the nAChR a4 subunit

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