1tf3

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[[Image:1tf3.gif|left|200px]]<br /><applet load="1tf3" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1tf3.gif|left|200px]]
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caption="1tf3" />
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'''TFIIIA FINGER 1-3 BOUND TO DNA, NMR, 22 STRUCTURES'''<br />
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{{Structure
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|PDB= 1tf3 |SIZE=350|CAPTION= <scene name='initialview01'>1tf3</scene>
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|SITE=
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|LIGAND= <scene name='pdbligand=ZN:ZINC ION'>ZN</scene>
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|ACTIVITY=
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|GENE=
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}}
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'''TFIIIA FINGER 1-3 BOUND TO DNA, NMR, 22 STRUCTURES'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1TF3 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis] with <scene name='pdbligand=ZN:'>ZN</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TF3 OCA].
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1TF3 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TF3 OCA].
==Reference==
==Reference==
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Domain packing and dynamics in the DNA complex of the N-terminal zinc fingers of TFIIIA., Foster MP, Wuttke DS, Radhakrishnan I, Case DA, Gottesfeld JM, Wright PE, Nat Struct Biol. 1997 Aug;4(8):605-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9253405 9253405]
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Domain packing and dynamics in the DNA complex of the N-terminal zinc fingers of TFIIIA., Foster MP, Wuttke DS, Radhakrishnan I, Case DA, Gottesfeld JM, Wright PE, Nat Struct Biol. 1997 Aug;4(8):605-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9253405 9253405]
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Xenopus laevis]]
[[Category: Xenopus laevis]]
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[[Category: zinc finger]]
[[Category: zinc finger]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:12:50 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:17:32 2008''

Revision as of 12:17, 20 March 2008


PDB ID 1tf3

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TFIIIA FINGER 1-3 BOUND TO DNA, NMR, 22 STRUCTURES


Overview

The three N-terminal zinc fingers of transcription factor IIIA bind in the DNA major groove. Substantial packing interfaces are formed between adjacent fingers, the linkers lose their intrinsic flexibility upon DNA binding, and several lysine side chains implicated in DNA recognition are dynamically disordered.

About this Structure

1TF3 is a Single protein structure of sequence from Xenopus laevis. Full crystallographic information is available from OCA.

Reference

Domain packing and dynamics in the DNA complex of the N-terminal zinc fingers of TFIIIA., Foster MP, Wuttke DS, Radhakrishnan I, Case DA, Gottesfeld JM, Wright PE, Nat Struct Biol. 1997 Aug;4(8):605-8. PMID:9253405

Page seeded by OCA on Thu Mar 20 14:17:32 2008

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