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2li8

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<StructureSection load='2li8' size='340' side='right' caption='[[2li8]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2li8' size='340' side='right' caption='[[2li8]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2li8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LI8 OCA]. <br>
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<table><tr><td colspan='2'>[[2li8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LI8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LI8 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2cqf|2cqf]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2cqf|2cqf]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CSDD1, Lin-28a, LIN28, LIN28A, ZCCHC1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CSDD1, Lin-28a, LIN28, LIN28A, ZCCHC1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2li8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2li8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2li8 RCSB], [http://www.ebi.ac.uk/pdbsum/2li8 PDBsum]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2li8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2li8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2li8 RCSB], [http://www.ebi.ac.uk/pdbsum/2li8 PDBsum]</span></td></tr>
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</table>
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<table>
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<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Structural basis of pre-let-7 miRNA recognition by the zinc knuckles of pluripotency factor Lin28.,Loughlin FE, Gebert LF, Towbin H, Brunschweiger A, Hall J, Allain FH Nat Struct Mol Biol. 2011 Dec 11;19(1):84-9. doi: 10.1038/nsmb.2202. PMID:22157959<ref>PMID:22157959</ref>
Structural basis of pre-let-7 miRNA recognition by the zinc knuckles of pluripotency factor Lin28.,Loughlin FE, Gebert LF, Towbin H, Brunschweiger A, Hall J, Allain FH Nat Struct Mol Biol. 2011 Dec 11;19(1):84-9. doi: 10.1038/nsmb.2202. PMID:22157959<ref>PMID:22157959</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
== References ==
== References ==
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Allain, F H.T.]]
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[[Category: Allain, F H.T]]
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[[Category: Loughlin, F E.]]
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[[Category: Loughlin, F E]]
[[Category: Micro rna]]
[[Category: Micro rna]]
[[Category: Transcription-rna complex]]
[[Category: Transcription-rna complex]]
[[Category: Zinc finger]]
[[Category: Zinc finger]]

Revision as of 06:26, 22 December 2014

The solution structure of the Lin28-ZnF domains bound to AGGAGAU of pre-let-7 miRNA

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