2lxu
From Proteopedia
(Difference between revisions)
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| - | [[ | + | ==Solution NMR Structure of the eukaryotic RNA recognition motif, RRM1, from the heterogeneous nuclear ribonucleoprotein H from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR8614A== |
| + | <StructureSection load='2lxu' size='340' side='right' caption='[[2lxu]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2lxu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LXU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LXU FirstGlance]. <br> | ||
| + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HNRNPH1, HNRPH, HNRPH1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lxu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lxu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lxu RCSB], [http://www.ebi.ac.uk/pdbsum/2lxu PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
| + | [[http://www.uniprot.org/uniprot/HNRH1_HUMAN HNRH1_HUMAN]] Precursor T-cell acute lymphoblastic leukemia. | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/HNRH1_HUMAN HNRH1_HUMAN]] This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Mediates pre-mRNA alternative splicing regulation. Inhibits, together with CUGBP1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast. Binds to the IR RNA. Binds poly(RG).<ref>PMID:11003644</ref> <ref>PMID:16946708</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Nucleoprotein|Nucleoprotein]] | |
| - | + | == References == | |
| - | + | <references/> | |
| - | + | __TOC__ | |
| - | == | + | </StructureSection> |
| - | + | [[Category: Human]] | |
| - | [[Category: | + | [[Category: Acton, T B]] |
| - | [[Category: Acton, T B | + | [[Category: Everett, J K]] |
| - | [[Category: Everett, J K | + | [[Category: Janjua, H]] |
| - | [[Category: Janjua, H | + | [[Category: Kennedy, M A]] |
| - | [[Category: Kennedy, M A | + | [[Category: Kohan, E]] |
| - | [[Category: Kohan, E | + | [[Category: Montelione, G T]] |
| - | [[Category: Montelione, G T | + | [[Category: Structural genomic]] |
| - | [[Category: | + | [[Category: Pederson, K]] |
| - | [[Category: Pederson, K | + | [[Category: Prestegard, J H]] |
| - | [[Category: Prestegard, J H | + | [[Category: Ramelot, T A]] |
| - | [[Category: Ramelot, T A | + | [[Category: Shastry, R]] |
| - | [[Category: Shastry, R | + | [[Category: Xiao, R]] |
| - | [[Category: Xiao, R | + | [[Category: Yang, Y]] |
| - | [[Category: Yang, Y | + | [[Category: PSI, Protein structure initiative]] |
| - | [[Category: Protein structure initiative]] | + | |
[[Category: Psi-biology]] | [[Category: Psi-biology]] | ||
[[Category: Rna binding protein]] | [[Category: Rna binding protein]] | ||
| - | [[Category: Structural genomic]] | ||
Revision as of 06:33, 22 December 2014
Solution NMR Structure of the eukaryotic RNA recognition motif, RRM1, from the heterogeneous nuclear ribonucleoprotein H from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR8614A
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