1tig
From Proteopedia
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| - | [[Image:1tig.gif|left|200px]] | + | [[Image:1tig.gif|left|200px]] |
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| - | '''TRANSLATION INITIATION FACTOR 3 C-TERMINAL DOMAIN''' | + | {{Structure |
| + | |PDB= 1tig |SIZE=350|CAPTION= <scene name='initialview01'>1tig</scene>, resolution 2.0Å | ||
| + | |SITE= | ||
| + | |LIGAND= | ||
| + | |ACTIVITY= | ||
| + | |GENE= T7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1422 Geobacillus stearothermophilus]) | ||
| + | }} | ||
| + | |||
| + | '''TRANSLATION INITIATION FACTOR 3 C-TERMINAL DOMAIN''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1TIG is a [ | + | 1TIG is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TIG OCA]. |
==Reference== | ==Reference== | ||
| - | X-ray crystallography shows that translational initiation factor IF3 consists of two compact alpha/beta domains linked by an alpha-helix., Biou V, Shu F, Ramakrishnan V, EMBO J. 1995 Aug 15;14(16):4056-64. PMID:[http:// | + | X-ray crystallography shows that translational initiation factor IF3 consists of two compact alpha/beta domains linked by an alpha-helix., Biou V, Shu F, Ramakrishnan V, EMBO J. 1995 Aug 15;14(16):4056-64. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7664745 7664745] |
[[Category: Geobacillus stearothermophilus]] | [[Category: Geobacillus stearothermophilus]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: if3 c-terminal domain]] | [[Category: if3 c-terminal domain]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:18:45 2008'' |
Revision as of 12:18, 20 March 2008
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| , resolution 2.0Å | |||||||
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| Gene: | T7 (Geobacillus stearothermophilus) | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
TRANSLATION INITIATION FACTOR 3 C-TERMINAL DOMAIN
Overview
The structures of the two domains of translational initiation factor IF3 from Bacillus stearothermophilus have been solved by X-ray crystallography using single wavelength anomalous scattering and multiwavelength anomalous diffraction. Each of the two domains has an alpha/beta topology, with an exposed beta-sheet that is reminiscent of several ribosomal and other RNA binding proteins. An alpha-helix that protrudes out from the body of the N-terminal domain towards the C-terminal domain suggests that IF3 consists of two RNA binding domains connected by an alpha-helix and that it may bridge two regions of the ribosome. This represents the first high resolution structural information on a translational initiation factor.
About this Structure
1TIG is a Single protein structure of sequence from Geobacillus stearothermophilus. Full crystallographic information is available from OCA.
Reference
X-ray crystallography shows that translational initiation factor IF3 consists of two compact alpha/beta domains linked by an alpha-helix., Biou V, Shu F, Ramakrishnan V, EMBO J. 1995 Aug 15;14(16):4056-64. PMID:7664745
Page seeded by OCA on Thu Mar 20 14:18:45 2008
