1an4

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1an4]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AN4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1AN4 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1an4]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AN4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1AN4 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1an4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1an4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1an4 RCSB], [http://www.ebi.ac.uk/pdbsum/1an4 PDBsum]</span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1an4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1an4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1an4 RCSB], [http://www.ebi.ac.uk/pdbsum/1an4 PDBsum]</span></td></tr>
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<table>
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</table>
== Disease ==
== Disease ==
[[http://www.uniprot.org/uniprot/USF1_HUMAN USF1_HUMAN]] Genetic variations in USF1 are associated with hyperlipidemia combined type 1 (HYPLIP1) [MIM:[http://omim.org/entry/602491 602491]]; also known as familial combined hyperlipidemia type 1 (FCHL1). HYPLIP1 is characterized by elevated levels of serum total cholesterol, triglycerides or both, and is observed in about 20% of individuals with premature coronary heart disease.<ref>PMID:14991056</ref>
[[http://www.uniprot.org/uniprot/USF1_HUMAN USF1_HUMAN]] Genetic variations in USF1 are associated with hyperlipidemia combined type 1 (HYPLIP1) [MIM:[http://omim.org/entry/602491 602491]]; also known as familial combined hyperlipidemia type 1 (FCHL1). HYPLIP1 is characterized by elevated levels of serum total cholesterol, triglycerides or both, and is observed in about 20% of individuals with premature coronary heart disease.<ref>PMID:14991056</ref>
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Amare, A R.Ferre-D.]]
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[[Category: Amare, A R.Ferre-D]]
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[[Category: Burley, S K.]]
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[[Category: Burley, S K]]
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[[Category: Pognonec, P.]]
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[[Category: Pognonec, P]]
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[[Category: Roeder, R G.]]
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[[Category: Roeder, R G]]
[[Category: Double helix]]
[[Category: Double helix]]
[[Category: Overhanging base]]
[[Category: Overhanging base]]
[[Category: Protein-dna complex]]
[[Category: Protein-dna complex]]
[[Category: Transcription-dna complex]]
[[Category: Transcription-dna complex]]

Revision as of 09:27, 22 December 2014

STRUCTURE AND FUNCTION OF THE B/HLH/Z DOMAIN OF USF

1an4, resolution 2.90Å

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