1tvt
From Proteopedia
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| - | [[Image:1tvt.jpg|left|200px]] | + | [[Image:1tvt.jpg|left|200px]] |
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| - | '''STRUCTURE OF THE EQUINE INFECTIOUS ANEMIA VIRUS TAT PROTEIN''' | + | {{Structure |
| + | |PDB= 1tvt |SIZE=350|CAPTION= <scene name='initialview01'>1tvt</scene> | ||
| + | |SITE= | ||
| + | |LIGAND= | ||
| + | |ACTIVITY= | ||
| + | |GENE= POTENTIAL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11665 Equine infectious anemia virus]) | ||
| + | }} | ||
| + | |||
| + | '''STRUCTURE OF THE EQUINE INFECTIOUS ANEMIA VIRUS TAT PROTEIN''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1TVT is a [ | + | 1TVT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Equine_infectious_anemia_virus Equine infectious anemia virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TVT OCA]. |
==Reference== | ==Reference== | ||
| - | Structure of the equine infectious anemia virus Tat protein., Willbold D, Rosin-Arbesfeld R, Sticht H, Frank R, Rosch P, Science. 1994 Jun 10;264(5165):1584-7. PMID:[http:// | + | Structure of the equine infectious anemia virus Tat protein., Willbold D, Rosin-Arbesfeld R, Sticht H, Frank R, Rosch P, Science. 1994 Jun 10;264(5165):1584-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7515512 7515512] |
[[Category: Equine infectious anemia virus]] | [[Category: Equine infectious anemia virus]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: transcription regulation]] | [[Category: transcription regulation]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:23:52 2008'' |
Revision as of 12:23, 20 March 2008
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| Gene: | POTENTIAL (Equine infectious anemia virus) | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
STRUCTURE OF THE EQUINE INFECTIOUS ANEMIA VIRUS TAT PROTEIN
Overview
Trans-activator (Tat) proteins regulate the transcription of lentiviral DNA in the host cell genome. These RNA binding proteins participate in the life cycle of all known lentiviruses, such as the human immunodeficiency viruses (HIV) or the equine infectious anemia virus (EIAV). The consensus RNA binding motifs [the trans-activation responsive element (TAR)] of HIV-1 as well as EIAV Tat proteins are well characterized. The structure of the 75-amino acid EIAV Tat protein in solution was determined by two- and three-dimensional nuclear magnetic resonance methods and molecular dynamics calculations. The protein structure exhibits a well-defined hydrophobic core of 15 amino acids that serves as a scaffold for two flexible domains corresponding to the NH2- and COOH-terminal regions. The core region is a strictly conserved sequence region among the known Tat proteins. The structural data can be used to explain several of the observed features of Tat proteins.
About this Structure
1TVT is a Single protein structure of sequence from Equine infectious anemia virus. Full crystallographic information is available from OCA.
Reference
Structure of the equine infectious anemia virus Tat protein., Willbold D, Rosin-Arbesfeld R, Sticht H, Frank R, Rosch P, Science. 1994 Jun 10;264(5165):1584-7. PMID:7515512
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