1tze
From Proteopedia
(Difference between revisions)
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| - | [[Image:1tze.jpg|left|200px]] | + | [[Image:1tze.jpg|left|200px]] |
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| - | '''SIGNAL TRANSDUCTION ADAPTOR GROWTH FACTOR, GRB2 SH2 DOMAIN COMPLEXED WITH PHOSPHOTYROSYL HEPTAPEPTIDE LYS-PRO-PHE-PTYR-VAL-ASN-VAL-NH2 (KFPPYVNC-NH2)''' | + | {{Structure |
| + | |PDB= 1tze |SIZE=350|CAPTION= <scene name='initialview01'>1tze</scene>, resolution 2.1Å | ||
| + | |SITE= | ||
| + | |LIGAND= <scene name='pdbligand=NH2:AMINO GROUP'>NH2</scene> | ||
| + | |ACTIVITY= | ||
| + | |GENE= GRB2 55-152 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | ||
| + | }} | ||
| + | |||
| + | '''SIGNAL TRANSDUCTION ADAPTOR GROWTH FACTOR, GRB2 SH2 DOMAIN COMPLEXED WITH PHOSPHOTYROSYL HEPTAPEPTIDE LYS-PRO-PHE-PTYR-VAL-ASN-VAL-NH2 (KFPPYVNC-NH2)''' | ||
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==Disease== | ==Disease== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1TZE is a [ | + | 1TZE is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TZE OCA]. |
==Reference== | ==Reference== | ||
| - | Structural basis for specificity of Grb2-SH2 revealed by a novel ligand binding mode., Rahuel J, Gay B, Erdmann D, Strauss A, Garcia-Echeverria C, Furet P, Caravatti G, Fretz H, Schoepfer J, Grutter MG, Nat Struct Biol. 1996 Jul;3(7):586-9. PMID:[http:// | + | Structural basis for specificity of Grb2-SH2 revealed by a novel ligand binding mode., Rahuel J, Gay B, Erdmann D, Strauss A, Garcia-Echeverria C, Furet P, Caravatti G, Fretz H, Schoepfer J, Grutter MG, Nat Struct Biol. 1996 Jul;3(7):586-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8673601 8673601] |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: signal transduction adaptor growth factor bound protein 2 (grb2) src homology 2 domain (sh2)]] | [[Category: signal transduction adaptor growth factor bound protein 2 (grb2) src homology 2 domain (sh2)]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:25:15 2008'' |
Revision as of 12:25, 20 March 2008
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| , resolution 2.1Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | |||||||
| Gene: | GRB2 55-152 (Homo sapiens) | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
SIGNAL TRANSDUCTION ADAPTOR GROWTH FACTOR, GRB2 SH2 DOMAIN COMPLEXED WITH PHOSPHOTYROSYL HEPTAPEPTIDE LYS-PRO-PHE-PTYR-VAL-ASN-VAL-NH2 (KFPPYVNC-NH2)
Disease
Known diseases associated with this structure: Central hypoventilation syndrome, congenital OMIM:[100790], Haddad syndrome OMIM:[100790]
About this Structure
1TZE is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Structural basis for specificity of Grb2-SH2 revealed by a novel ligand binding mode., Rahuel J, Gay B, Erdmann D, Strauss A, Garcia-Echeverria C, Furet P, Caravatti G, Fretz H, Schoepfer J, Grutter MG, Nat Struct Biol. 1996 Jul;3(7):586-9. PMID:8673601
Page seeded by OCA on Thu Mar 20 14:25:15 2008
