1buy

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1buy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BUY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BUY FirstGlance]. <br>
<table><tr><td colspan='2'>[[1buy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BUY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BUY FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1buy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1buy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1buy RCSB], [http://www.ebi.ac.uk/pdbsum/1buy PDBsum]</span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1buy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1buy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1buy RCSB], [http://www.ebi.ac.uk/pdbsum/1buy PDBsum]</span></td></tr>
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<table>
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</table>
== Disease ==
== Disease ==
[[http://www.uniprot.org/uniprot/EPO_HUMAN EPO_HUMAN]] Genetic variation in EPO is associated with susceptbility to microvascular complications of diabetes type 2 (MVCD2) [MIM:[http://omim.org/entry/612623 612623]]. These are pathological conditions that develop in numerous tissues and organs as a consequence of diabetes mellitus. They include diabetic retinopathy, diabetic nephropathy leading to end-stage renal disease, and diabetic neuropathy. Diabetic retinopathy remains the major cause of new-onset blindness among diabetic adults. It is characterized by vascular permeability and increased tissue ischemia and angiogenesis.
[[http://www.uniprot.org/uniprot/EPO_HUMAN EPO_HUMAN]] Genetic variation in EPO is associated with susceptbility to microvascular complications of diabetes type 2 (MVCD2) [MIM:[http://omim.org/entry/612623 612623]]. These are pathological conditions that develop in numerous tissues and organs as a consequence of diabetes mellitus. They include diabetic retinopathy, diabetic nephropathy leading to end-stage renal disease, and diabetic neuropathy. Diabetic retinopathy remains the major cause of new-onset blindness among diabetic adults. It is characterized by vascular permeability and increased tissue ischemia and angiogenesis.
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Aoki, K H.]]
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[[Category: Aoki, K H]]
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[[Category: Cheetham, J C.]]
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[[Category: Cheetham, J C]]
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[[Category: Egrie, J.]]
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[[Category: Egrie, J]]
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[[Category: Harvey, T S.]]
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[[Category: Harvey, T S]]
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[[Category: Hoeffel, T J.]]
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[[Category: Hoeffel, T J]]
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[[Category: Smith, D M.]]
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[[Category: Smith, D M]]
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[[Category: Stevenson, J L.]]
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[[Category: Stevenson, J L]]
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[[Category: Syed, R S.]]
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[[Category: Syed, R S]]
[[Category: Cytokine]]
[[Category: Cytokine]]
[[Category: Glycoprotein]]
[[Category: Glycoprotein]]
[[Category: Growth factor]]
[[Category: Growth factor]]

Revision as of 10:59, 22 December 2014

HUMAN ERYTHROPOIETIN, NMR MINIMIZED AVERAGE STRUCTURE

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