1u9s
From Proteopedia
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- | [[Image:1u9s.gif|left|200px]] | + | [[Image:1u9s.gif|left|200px]] |
- | + | ||
- | '''Crystal structure of the specificity domain of Ribonuclease P of the A-type''' | + | {{Structure |
+ | |PDB= 1u9s |SIZE=350|CAPTION= <scene name='initialview01'>1u9s</scene>, resolution 2.90Å | ||
+ | |SITE= | ||
+ | |LIGAND= <scene name='pdbligand=BA:BARIUM ION'>BA</scene> | ||
+ | |ACTIVITY= | ||
+ | |GENE= | ||
+ | }} | ||
+ | |||
+ | '''Crystal structure of the specificity domain of Ribonuclease P of the A-type''' | ||
+ | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
- | 1U9S is a [ | + | 1U9S is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U9S OCA]. |
==Reference== | ==Reference== | ||
- | Basis for structural diversity in homologous RNAs., Krasilnikov AS, Xiao Y, Pan T, Mondragon A, Science. 2004 Oct 1;306(5693):104-7. PMID:[http:// | + | Basis for structural diversity in homologous RNAs., Krasilnikov AS, Xiao Y, Pan T, Mondragon A, Science. 2004 Oct 1;306(5693):104-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15459389 15459389] |
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Krasilnikov, A S.]] | [[Category: Krasilnikov, A S.]] | ||
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[[Category: trna]] | [[Category: trna]] | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:29:07 2008'' |
Revision as of 12:29, 20 March 2008
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, resolution 2.90Å | |||||||
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Coordinates: | save as pdb, mmCIF, xml |
Crystal structure of the specificity domain of Ribonuclease P of the A-type
Overview
Large RNA molecules, such as ribozymes, fold with well-defined tertiary structures that are important for their activity. There are many instances of ribozymes with identical function but differences in their secondary structures, suggesting alternative tertiary folds. Here, we report a crystal structure of the 161-nucleotide specificity domain of an A-type ribonuclease P that differs in secondary and tertiary structure from the specificity domain of a B-type molecule. Despite the differences, the cores of the domains have similar three-dimensional structure. Remarkably, the similar geometry of the cores is stabilized by a different set of interactions involving distinct auxiliary elements.
About this Structure
1U9S is a Single protein structure of sequence from [1]. Full crystallographic information is available from OCA.
Reference
Basis for structural diversity in homologous RNAs., Krasilnikov AS, Xiao Y, Pan T, Mondragon A, Science. 2004 Oct 1;306(5693):104-7. PMID:15459389
Page seeded by OCA on Thu Mar 20 14:29:07 2008
Categories: Single protein | Krasilnikov, A S. | Mondragon, A. | Pan, T. | Xiao, Y. | BA | P rna | Pre-trna | Ribonuclease p rna | Ribozyme | Rnase p | S-domain | Specificity domain | Thermus thermophilus | Trna