1hcf

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1hcf]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HCF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HCF FirstGlance]. <br>
<table><tr><td colspan='2'>[[1hcf]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HCF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HCF FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1wwb|1wwb]], [[1b8m|1b8m]], [[1b98|1b98]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1wwb|1wwb]], [[1b8m|1b8m]], [[1b98|1b98]]</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hcf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hcf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1hcf RCSB], [http://www.ebi.ac.uk/pdbsum/1hcf PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hcf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hcf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1hcf RCSB], [http://www.ebi.ac.uk/pdbsum/1hcf PDBsum]</span></td></tr>
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<table>
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</table>
== Disease ==
== Disease ==
[[http://www.uniprot.org/uniprot/NTF4_HUMAN NTF4_HUMAN]] Defects in NTF4 may be associated with susceptibility to primary open angle glaucoma type 1O (GLC1O) [MIM:[http://omim.org/entry/613100 613100]]. A form of primary open angle glaucoma (POAG). POAG is characterized by a specific pattern of optic nerve and visual field defects. The angle of the anterior chamber of the eye is open, and usually the intraocular pressure is increased. The disease is asymptomatic until the late stages, by which time significant and irreversible optic nerve damage has already taken place.
[[http://www.uniprot.org/uniprot/NTF4_HUMAN NTF4_HUMAN]] Defects in NTF4 may be associated with susceptibility to primary open angle glaucoma type 1O (GLC1O) [MIM:[http://omim.org/entry/613100 613100]]. A form of primary open angle glaucoma (POAG). POAG is characterized by a specific pattern of optic nerve and visual field defects. The angle of the anterior chamber of the eye is open, and usually the intraocular pressure is increased. The disease is asymptomatic until the late stages, by which time significant and irreversible optic nerve damage has already taken place.
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Allen, S J.]]
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[[Category: Allen, S J]]
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[[Category: Banfield, M J.]]
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[[Category: Banfield, M J]]
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[[Category: Brady, R L.]]
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[[Category: Brady, R L]]
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[[Category: Dawbarn, D.]]
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[[Category: Dawbarn, D]]
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[[Category: Naylor, R L.]]
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[[Category: Naylor, R L]]
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[[Category: Robertson, A G.S.]]
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[[Category: Robertson, A G.S]]
[[Category: Immunoglobulin domain]]
[[Category: Immunoglobulin domain]]
[[Category: Neurotrophin-4/5]]
[[Category: Neurotrophin-4/5]]

Revision as of 18:23, 22 December 2014

CRYSTAL STRUCTURE OF TRKB-D5 BOUND TO NEUROTROPHIN-4/5

1hcf, resolution 2.70Å

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