1uhn

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[[Image:1uhn.jpg|left|200px]]<br /><applet load="1uhn" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1uhn.jpg|left|200px]]
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caption="1uhn, resolution 2.1&Aring;" />
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'''The crystal structure of the calcium binding protein AtCBL2 from Arabidopsis thaliana'''<br />
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{{Structure
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|PDB= 1uhn |SIZE=350|CAPTION= <scene name='initialview01'>1uhn</scene>, resolution 2.1&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=CA:CALCIUM ION'>CA</scene>
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|ACTIVITY=
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|GENE=
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}}
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'''The crystal structure of the calcium binding protein AtCBL2 from Arabidopsis thaliana'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1UHN is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana] with <scene name='pdbligand=CA:'>CA</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UHN OCA].
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1UHN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UHN OCA].
==Reference==
==Reference==
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The crystal structure of the novel calcium-binding protein AtCBL2 from Arabidopsis thaliana., Nagae M, Nozawa A, Koizumi N, Sano H, Hashimoto H, Sato M, Shimizu T, J Biol Chem. 2003 Oct 24;278(43):42240-6. Epub 2003 Jul 19. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12871972 12871972]
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The crystal structure of the novel calcium-binding protein AtCBL2 from Arabidopsis thaliana., Nagae M, Nozawa A, Koizumi N, Sano H, Hashimoto H, Sato M, Shimizu T, J Biol Chem. 2003 Oct 24;278(43):42240-6. Epub 2003 Jul 19. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12871972 12871972]
[[Category: Arabidopsis thaliana]]
[[Category: Arabidopsis thaliana]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: calcium binding protein]]
[[Category: calcium binding protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:24:37 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:32:08 2008''

Revision as of 12:32, 20 March 2008


PDB ID 1uhn

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, resolution 2.1Å
Ligands:
Coordinates: save as pdb, mmCIF, xml



The crystal structure of the calcium binding protein AtCBL2 from Arabidopsis thaliana


Overview

Arabidopsis thaliana calcineurin B-like protein (AtCBL2) is a member of a recently identified family of calcineurin B-like calcium-binding proteins in A. thaliana. The crystal structure of AtCBL2 has been determined at 2.1 A resolution. The protein forms a compact alpha-helical structure with two pairs of EF-hand motifs. The structure is similar in overall folding topology to the structures of calcineurin B and neuronal calcium sensor 1, but differs significantly in local conformation. The two calcium ions are coordinated in the first and fourth EF-hand motifs, whereas the second and third EF-hand motifs are maintained in the open form by internal hydrogen bonding without coordination of calcium ions. Both a possible site and a possible mechanism for the target binding to AtCBL2 are discussed based on the three-dimensional structure.

About this Structure

1UHN is a Single protein structure of sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA.

Reference

The crystal structure of the novel calcium-binding protein AtCBL2 from Arabidopsis thaliana., Nagae M, Nozawa A, Koizumi N, Sano H, Hashimoto H, Sato M, Shimizu T, J Biol Chem. 2003 Oct 24;278(43):42240-6. Epub 2003 Jul 19. PMID:12871972

Page seeded by OCA on Thu Mar 20 14:32:08 2008

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