This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1hiv
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1hiv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HIV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HIV FirstGlance]. <br> | <table><tr><td colspan='2'>[[1hiv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HIV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HIV FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1ZK:4-[(2R)-3-{[(1S,2S,3R,4S)-1-(CYCLOHEXYLMETHYL)-2,3-DIHYDROXY-5-METHYL-4-({(1S,2R)-2-METHYL-1-[(PYRIDIN-2-YLMETHYL)CARBAMOYL]BUTYL}CARBAMOYL)HEXYL]AMINO}-2-{[(NAPHTHALEN-1-YLOXY)ACETYL]AMINO}-3-OXOPROPYL]-1H-IMIDAZOL-3-IUM'>1ZK</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1ZK:4-[(2R)-3-{[(1S,2S,3R,4S)-1-(CYCLOHEXYLMETHYL)-2,3-DIHYDROXY-5-METHYL-4-({(1S,2R)-2-METHYL-1-[(PYRIDIN-2-YLMETHYL)CARBAMOYL]BUTYL}CARBAMOYL)HEXYL]AMINO}-2-{[(NAPHTHALEN-1-YLOXY)ACETYL]AMINO}-3-OXOPROPYL]-1H-IMIDAZOL-3-IUM'>1ZK</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr> | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hiv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hiv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1hiv RCSB], [http://www.ebi.ac.uk/pdbsum/1hiv PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hiv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hiv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1hiv RCSB], [http://www.ebi.ac.uk/pdbsum/1hiv PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 30: | Line 30: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human immunodeficiency virus 1]] | [[Category: Human immunodeficiency virus 1]] | ||
| - | [[Category: Thanki, N | + | [[Category: Thanki, N]] |
| - | [[Category: Wlodawer, A | + | [[Category: Wlodawer, A]] |
[[Category: Acid proteinase]] | [[Category: Acid proteinase]] | ||
[[Category: Hydrolase-hydrolase inhibitor complex]] | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
Revision as of 19:55, 22 December 2014
CRYSTAL STRUCTURE OF A COMPLEX OF HIV-1 PROTEASE WITH A DIHYDROETHYLENE-CONTAINING INHIBITOR: COMPARISONS WITH MOLECULAR MODELING
| |||||||||||
