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1uvw

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[[Image:1uvw.gif|left|200px]]<br /><applet load="1uvw" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1uvw.gif|left|200px]]
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caption="1uvw, resolution 2.45&Aring;" />
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'''BACILLUS SUBTILIS COTA LACCASE ADDUCT WITH ABTS'''<br />
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{{Structure
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|PDB= 1uvw |SIZE=350|CAPTION= <scene name='initialview01'>1uvw</scene>, resolution 2.45&Aring;
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|SITE= <scene name='pdbsite=AC1:Gol+Binding+Site+For+Chain+A'>AC1</scene>
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|LIGAND= <scene name='pdbligand=CU1:COPPER+(I)+ION'>CU1</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene>, <scene name='pdbligand=EBS:3-ETHYL-2-[(2Z)-2-(3-ETHYL-6-SULFO-1,3-BENZOTHIAZOL-2(3H)-YLIDENE)HYDRAZINO]-6-SULFO-3H-1,3-BENZOTHIAZOL-1-IUM'>EBS</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
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|ACTIVITY=
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|GENE=
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}}
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'''BACILLUS SUBTILIS COTA LACCASE ADDUCT WITH ABTS'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1UVW is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis] with <scene name='pdbligand=CU1:'>CU1</scene>, <scene name='pdbligand=OXY:'>OXY</scene>, <scene name='pdbligand=EBS:'>EBS</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Known structural/functional Site: <scene name='pdbsite=AC1:Gol+Binding+Site+For+Chain+A'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UVW OCA].
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1UVW is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UVW OCA].
==Reference==
==Reference==
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Substrate and dioxygen binding to the endospore coat laccase from Bacillus subtilis., Enguita FJ, Marcal D, Martins LO, Grenha R, Henriques AO, Lindley PF, Carrondo MA, J Biol Chem. 2004 May 28;279(22):23472-6. Epub 2004 Feb 4. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=14764581 14764581]
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Substrate and dioxygen binding to the endospore coat laccase from Bacillus subtilis., Enguita FJ, Marcal D, Martins LO, Grenha R, Henriques AO, Lindley PF, Carrondo MA, J Biol Chem. 2004 May 28;279(22):23472-6. Epub 2004 Feb 4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14764581 14764581]
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: GOL]]
[[Category: GOL]]
[[Category: OXY]]
[[Category: OXY]]
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[[Category: bacillus subtilis]]
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[[Category: bacillus subtili]]
[[Category: laccase]]
[[Category: laccase]]
[[Category: multicopper oxidase]]
[[Category: multicopper oxidase]]
[[Category: sporulation]]
[[Category: sporulation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:29:01 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:37:28 2008''

Revision as of 12:37, 20 March 2008

Image:1uvw.gif


PDB ID 1uvw

Drag the structure with the mouse to rotate
, resolution 2.45Å
Sites:
Ligands: , , and
Coordinates: save as pdb, mmCIF, xml



BACILLUS SUBTILIS COTA LACCASE ADDUCT WITH ABTS


Overview

The CotA laccase from the endospore coat of Bacillus subtilis has been crystallized in the presence of the non-catalytic co-oxidant 2,2'-azinobis-(3-ethylbenzothiazoline-6-sulfonate) (ABTS), and the structure was determined using synchrotron radiation. The binding site for this adduct is well defined and indicates how ABTS, in conjunction with laccases, could act as an oxidative mediator toward non-phenolic moieties. In addition, a dioxygen moiety is clearly defined within the solvent channel oriented toward one of the T3 copper atoms in the trinuclear center.

About this Structure

1UVW is a Single protein structure of sequence from Bacillus subtilis. Full crystallographic information is available from OCA.

Reference

Substrate and dioxygen binding to the endospore coat laccase from Bacillus subtilis., Enguita FJ, Marcal D, Martins LO, Grenha R, Henriques AO, Lindley PF, Carrondo MA, J Biol Chem. 2004 May 28;279(22):23472-6. Epub 2004 Feb 4. PMID:14764581

Page seeded by OCA on Thu Mar 20 14:37:28 2008

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