1h5u
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1h5u]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H5U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1H5U FirstGlance]. <br> | <table><tr><td colspan='2'>[[1h5u]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H5U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1H5U FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CHI:5-CHLORO-1H-INDOLE-2-CARBOXYLIC+ACID+[1-(4-FLUOROBENZYL)-2-(4-HYDROXYPIPERIDIN-1YL)-2-OXOETHYL]AMIDE'>CHI</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CHI:5-CHLORO-1H-INDOLE-2-CARBOXYLIC+ACID+[1-(4-FLUOROBENZYL)-2-(4-HYDROXYPIPERIDIN-1YL)-2-OXOETHYL]AMIDE'>CHI</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1a8i|1a8i]], [[1abb|1abb]], [[1axr|1axr]], [[1b4d|1b4d]], [[1bx3|1bx3]], [[1c50|1c50]], [[1c8k|1c8k]], [[1c8l|1c8l]], [[1e1y|1e1y]], [[1fs4|1fs4]], [[1ftq|1ftq]], [[1ftw|1ftw]], [[1fty|1fty]], [[1fu4|1fu4]], [[1fu7|1fu7]], [[1fu8|1fu8]], [[1gfz|1gfz]], [[1gg8|1gg8]], [[1ggn|1ggn]], [[1gpa|1gpa]], [[1gpb|1gpb]], [[1gpy|1gpy]], [[1hlf|1hlf]], [[1noi|1noi]], [[1noj|1noj]], [[1nok|1nok]], [[1pyg|1pyg]], [[2amv|2amv]], [[2gpa|2gpa]], [[2gpb|2gpb]], [[2gpn|2gpn]], [[2pri|2pri]], [[2prj|2prj]], [[2skc|2skc]], [[2skd|2skd]], [[2ske|2ske]], [[3amv|3amv]], [[3gpb|3gpb]], [[4gpb|4gpb]], [[5gpb|5gpb]], [[6gpb|6gpb]], [[7gpb|7gpb]], [[8gpb|8gpb]], [[9gpb|9gpb]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1a8i|1a8i]], [[1abb|1abb]], [[1axr|1axr]], [[1b4d|1b4d]], [[1bx3|1bx3]], [[1c50|1c50]], [[1c8k|1c8k]], [[1c8l|1c8l]], [[1e1y|1e1y]], [[1fs4|1fs4]], [[1ftq|1ftq]], [[1ftw|1ftw]], [[1fty|1fty]], [[1fu4|1fu4]], [[1fu7|1fu7]], [[1fu8|1fu8]], [[1gfz|1gfz]], [[1gg8|1gg8]], [[1ggn|1ggn]], [[1gpa|1gpa]], [[1gpb|1gpb]], [[1gpy|1gpy]], [[1hlf|1hlf]], [[1noi|1noi]], [[1noj|1noj]], [[1nok|1nok]], [[1pyg|1pyg]], [[2amv|2amv]], [[2gpa|2gpa]], [[2gpb|2gpb]], [[2gpn|2gpn]], [[2pri|2pri]], [[2prj|2prj]], [[2skc|2skc]], [[2skd|2skd]], [[2ske|2ske]], [[3amv|3amv]], [[3gpb|3gpb]], [[4gpb|4gpb]], [[5gpb|5gpb]], [[6gpb|6gpb]], [[7gpb|7gpb]], [[8gpb|8gpb]], [[9gpb|9gpb]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphorylase Phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.1 2.4.1.1] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphorylase Phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.1 2.4.1.1] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1h5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h5u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1h5u RCSB], [http://www.ebi.ac.uk/pdbsum/1h5u PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1h5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h5u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1h5u RCSB], [http://www.ebi.ac.uk/pdbsum/1h5u PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Oryctolagus cuniculus]] | [[Category: Oryctolagus cuniculus]] | ||
[[Category: Phosphorylase]] | [[Category: Phosphorylase]] | ||
| - | [[Category: Archontis, G | + | [[Category: Archontis, G]] |
| - | [[Category: Oikonomakos, N G | + | [[Category: Oikonomakos, N G]] |
| - | [[Category: Skamnaki, V T | + | [[Category: Skamnaki, V T]] |
| - | [[Category: Zographos, S E | + | [[Category: Zographos, S E]] |
[[Category: Central cavity]] | [[Category: Central cavity]] | ||
[[Category: Drug binding site]] | [[Category: Drug binding site]] | ||
Revision as of 00:32, 23 December 2014
THE 1.76 A RESOLUTION CRYSTAL STRUCTURE OF GLYCOGEN PHOSPHORYLASE B COMPLEXED WITH GLUCOSE AND CP320626, A POTENTIAL ANTIDIABETIC DRUG
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