Sandbox Reserved 959

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<scene name='60/604478/Hydrophobe/1'>hydrophobes</scene>
=== References ===
=== References ===

Revision as of 14:09, 23 December 2014

This Sandbox is Reserved from 06/12/2018, through 30/06/2019 for use in the course "Structural Biology" taught by Bruno Kieffer at the University of Strasbourg, ESBS. This reservation includes Sandbox Reserved 1480 through Sandbox Reserved 1543.
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Defensins-α-1


Introduction

Defensins (DEF) are a family of protein which are involved in host defenses in the epithelia of mucosal surfaces such as those of the intestin, respiratory tract, urinary tract, and vagina. There are antimicrobial and cytotoxic. All the protein of the family are distinguished by a cystein motif and are encoded on the chromozome 8.
[1]. There are many defensin but in this article we will focus on the defensin-α-1. The defensin-α-1 is a polypeptide which is found in the microbicidal granules of neutrophils. It's syntetisize in the paneth cell, which plays a role in the defense process. [2]It plays a role in phagocite-mediated host defense.
In this article, we will focus on the action of the defensin-α-1 against the "trypanosoma cruzy".

PDB ID 2pm4

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