4pj6

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pj6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pj6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pj6 RCSB], [http://www.ebi.ac.uk/pdbsum/4pj6 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pj6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pj6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pj6 RCSB], [http://www.ebi.ac.uk/pdbsum/4pj6 PDBsum]</span></td></tr>
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== Function ==
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[[http://www.uniprot.org/uniprot/LCAP_HUMAN LCAP_HUMAN]] Release of an N-terminal amino acid, cleaves before cysteine, leucine as well as other amino acids. Degrades peptide hormones such as oxytocin, vasopressin and angiotensin III, and plays a role in maintaining homeostasis during pregnancy. May be involved in the inactivation of neuronal peptides in the brain. Cleaves Met-enkephalin and dynorphin. Binds angiotensin IV and may be the angiotensin IV receptor in the brain.<ref>PMID:11389728</ref> <ref>PMID:11707427</ref> <ref>PMID:1731608</ref>
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==

Revision as of 06:52, 24 December 2014

Crystal Structure of Human Insulin Regulated Aminopeptidase with Lysine in Active Site

4pj6, resolution 2.96Å

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