4kij
From Proteopedia
(Difference between revisions)
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<StructureSection load='4kij' size='340' side='right' caption='[[4kij]], [[Resolution|resolution]] 2.80Å' scene=''> | <StructureSection load='4kij' size='340' side='right' caption='[[4kij]], [[Resolution|resolution]] 2.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4kij]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KIJ OCA]. <br> | + | <table><tr><td colspan='2'>[[4kij]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KIJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KIJ FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=KIJ:3,4-DIHYDROXY-5-(3-NITROPHENOXY)BENZOIC+ACID'>KIJ</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=KIJ:3,4-DIHYDROXY-5-(3-NITROPHENOXY)BENZOIC+ACID'>KIJ</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ki7|4ki7]], [[4kim|4kim]], [[4kiu|4kiu]], [[4kiw|4kiw]], [[4kl9|4kl9]], [[4klx|4klx]], [[4km0|4km0]], [[4km2|4km2]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ki7|4ki7]], [[4kim|4kim]], [[4kiu|4kiu]], [[4kiw|4kiw]], [[4kl9|4kl9]], [[4klx|4klx]], [[4km0|4km0]], [[4km2|4km2]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-dehydroquinate_dehydratase 3-dehydroquinate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.10 4.2.1.10] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kij FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kij OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kij RCSB], [http://www.ebi.ac.uk/pdbsum/4kij PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kij FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kij OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kij RCSB], [http://www.ebi.ac.uk/pdbsum/4kij PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/AROQ_MYCTU AROQ_MYCTU]] Catalyzes a trans-dehydration via an enolate intermediate (By similarity).[HAMAP-Rule:MF_00169] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: 3-dehydroquinate dehydratase]] | [[Category: 3-dehydroquinate dehydratase]] | ||
| - | [[Category: Abell, C | + | [[Category: Abell, C]] |
| - | [[Category: Blundell, T L | + | [[Category: Blundell, T L]] |
[[Category: Dias, M V.B]] | [[Category: Dias, M V.B]] | ||
| - | [[Category: Howard, N G | + | [[Category: Howard, N G]] |
[[Category: Dehydratase]] | [[Category: Dehydratase]] | ||
[[Category: Lyase-lyase inhibitor complex]] | [[Category: Lyase-lyase inhibitor complex]] | ||
Revision as of 06:53, 24 December 2014
Design and structural analysis of aromatic inhibitors of type II dehydroquinase dehydratase from Mycobacterium tuberculosis - compound 35c [3,4-dihydroxy-5-(3-nitrophenoxy)benzoic acid]
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