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2xda

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2xda]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XDA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XDA FirstGlance]. <br>
<table><tr><td colspan='2'>[[2xda]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XDA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XDA FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=JPS:(4R,6R,7S)-2-(2-CYCLOPROPYLETHYL)-4,6,7-TRIHYDROXY-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-4-CARBOXYLIC+ACID'>JPS</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=JPS:(4R,6R,7S)-2-(2-CYCLOPROPYLETHYL)-4,6,7-TRIHYDROXY-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-4-CARBOXYLIC+ACID'>JPS</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2c57|2c57]], [[2wks|2wks]], [[2c4v|2c4v]], [[1j2y|1j2y]], [[2xb9|2xb9]], [[2c4w|2c4w]], [[2xd9|2xd9]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2c57|2c57]], [[2wks|2wks]], [[2c4v|2c4v]], [[1j2y|1j2y]], [[2xb9|2xb9]], [[2c4w|2c4w]], [[2xd9|2xd9]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-dehydroquinate_dehydratase 3-dehydroquinate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.10 4.2.1.10] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-dehydroquinate_dehydratase 3-dehydroquinate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.10 4.2.1.10] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xda FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xda OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xda RCSB], [http://www.ebi.ac.uk/pdbsum/2xda PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xda FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xda OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xda RCSB], [http://www.ebi.ac.uk/pdbsum/2xda PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/AROQ_HELPY AROQ_HELPY]] Catalyzes a trans-dehydration via an enolate intermediate (By similarity).[HAMAP-Rule:MF_00169]
==See Also==
==See Also==
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[[Category: 3-dehydroquinate dehydratase]]
[[Category: 3-dehydroquinate dehydratase]]
[[Category: Helicobacter pylori]]
[[Category: Helicobacter pylori]]
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[[Category: Castedo, L.]]
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[[Category: Castedo, L]]
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[[Category: Fox, G C.]]
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[[Category: Fox, G C]]
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[[Category: Gonzalez-Bello, C.]]
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[[Category: Gonzalez-Bello, C]]
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[[Category: Hawkins, A R.]]
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[[Category: Hawkins, A R]]
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[[Category: Lamb, H.]]
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[[Category: Lamb, H]]
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[[Category: Llamas-Saiz, A L.]]
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[[Category: Llamas-Saiz, A L]]
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[[Category: Otero, J M.]]
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[[Category: Otero, J M]]
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[[Category: Paz, S.]]
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[[Category: Paz, S]]
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[[Category: Raaij, M J.Van.]]
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[[Category: Raaij, M J.Van]]
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[[Category: Tizon, L.]]
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[[Category: Tizon, L]]
[[Category: Aromatic amino acid biosynthesis]]
[[Category: Aromatic amino acid biosynthesis]]
[[Category: Lyase]]
[[Category: Lyase]]

Revision as of 06:54, 24 December 2014

STRUCTURE OF HELICOBACTER PYLORI TYPE II DEHYDROQUINASE IN COMPLEX WITH INHIBITOR COMPOUND (4R,6R,7S)-2-(2-Cyclopropyl)ethyl-4,6,7- trihydroxy-4,5,6,7-tetrahydrobenzo(b)thiophene-4-carboxylic acid

2xda, resolution 1.85Å

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