1vp3

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[[Image:1vp3.jpg|left|200px]]<br /><applet load="1vp3" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1vp3.jpg|left|200px]]
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caption="1vp3, resolution 1.9&Aring;" />
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'''VACCINIA VIRUS PROTEIN VP39 IN COMPLEX WITH S-ADENOSYLHOMOCYSTEINE'''<br />
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{{Structure
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|PDB= 1vp3 |SIZE=350|CAPTION= <scene name='initialview01'>1vp3</scene>, resolution 1.9&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Polynucleotide_adenylyltransferase Polynucleotide adenylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.19 2.7.7.19]
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|GENE=
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}}
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'''VACCINIA VIRUS PROTEIN VP39 IN COMPLEX WITH S-ADENOSYLHOMOCYSTEINE'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1VP3 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Vaccinia_virus Vaccinia virus] with <scene name='pdbligand=SAH:'>SAH</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Polynucleotide_adenylyltransferase Polynucleotide adenylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.19 2.7.7.19] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VP3 OCA].
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1VP3 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Vaccinia_virus Vaccinia virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VP3 OCA].
==Reference==
==Reference==
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Specific protein recognition of an mRNA cap through its alkylated base., Hodel AE, Gershon PD, Shi X, Wang SM, Quiocho FA, Nat Struct Biol. 1997 May;4(5):350-4. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9145102 9145102]
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Specific protein recognition of an mRNA cap through its alkylated base., Hodel AE, Gershon PD, Shi X, Wang SM, Quiocho FA, Nat Struct Biol. 1997 May;4(5):350-4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9145102 9145102]
[[Category: Polynucleotide adenylyltransferase]]
[[Category: Polynucleotide adenylyltransferase]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: vaccinia]]
[[Category: vaccinia]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:37:13 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:47:55 2008''

Revision as of 12:47, 20 March 2008

Image:1vp3.jpg


PDB ID 1vp3

Drag the structure with the mouse to rotate
, resolution 1.9Å
Ligands:
Activity: Polynucleotide adenylyltransferase, with EC number 2.7.7.19
Coordinates: save as pdb, mmCIF, xml



VACCINIA VIRUS PROTEIN VP39 IN COMPLEX WITH S-ADENOSYLHOMOCYSTEINE


Overview

The specific binding of N7-methylguanine cap analogues to the RNA methyltransferase VP39 was observed through X-ray crystallography, providing a prototypical structure for a complex between a protein and an mRNA 5' cap.

About this Structure

1VP3 is a Single protein structure of sequence from Vaccinia virus. Full crystallographic information is available from OCA.

Reference

Specific protein recognition of an mRNA cap through its alkylated base., Hodel AE, Gershon PD, Shi X, Wang SM, Quiocho FA, Nat Struct Biol. 1997 May;4(5):350-4. PMID:9145102

Page seeded by OCA on Thu Mar 20 14:47:55 2008

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