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2hyw

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2hyw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HYW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HYW FirstGlance]. <br>
<table><tr><td colspan='2'>[[2hyw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HYW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HYW FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ANXA2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ANXA2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hyw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hyw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2hyw RCSB], [http://www.ebi.ac.uk/pdbsum/2hyw PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hyw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hyw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2hyw RCSB], [http://www.ebi.ac.uk/pdbsum/2hyw PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/ANXA2_HUMAN ANXA2_HUMAN]] Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Head, J F.]]
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[[Category: Head, J F]]
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[[Category: Seaton, B A.]]
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[[Category: Seaton, B A]]
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[[Category: Shao, C.]]
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[[Category: Shao, C]]
[[Category: Calcium-binding protein]]
[[Category: Calcium-binding protein]]
[[Category: Helix bundle]]
[[Category: Helix bundle]]
[[Category: Membrane-binding protein]]
[[Category: Membrane-binding protein]]
[[Category: Metal binding protein]]
[[Category: Metal binding protein]]

Revision as of 07:20, 24 December 2014

Human Annexin A2 with Calcium bound

2hyw, resolution 2.10Å

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