3pv6
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pv6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pv6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3pv6 RCSB], [http://www.ebi.ac.uk/pdbsum/3pv6 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pv6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pv6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3pv6 RCSB], [http://www.ebi.ac.uk/pdbsum/3pv6 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/YK047_HUMAN YK047_HUMAN]] Triggers NCR3-dependent natural killer cell activation.<ref>PMID:19528259</ref> [[http://www.uniprot.org/uniprot/NCTR3_HUMAN NCTR3_HUMAN]] Cytotoxicity-activating receptor that contributes to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. Engagement of NCR3 by BAG6 also promotes dendritic cell (DC) maturation, both through killing those DCs that did not properly acquire a mature phenotype, and inducing NK cells to release TNFA and IFNG, which promotes DC maturation.<ref>PMID:10562324</ref> <ref>PMID:15784725</ref> <ref>PMID:18852879</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 07:59, 24 December 2014
Crystal structure of NKp30 bound to its ligand B7-H6
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