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1xwj
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1xwj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XWJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XWJ FirstGlance]. <br> | <table><tr><td colspan='2'>[[1xwj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XWJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XWJ FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xwj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xwj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xwj RCSB], [http://www.ebi.ac.uk/pdbsum/1xwj PDBsum]</span></td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xwj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xwj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xwj RCSB], [http://www.ebi.ac.uk/pdbsum/1xwj PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/VINC_CHICK VINC_CHICK]] Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.<ref>PMID:15229287</ref> <ref>PMID:20584916</ref> <ref>PMID:20086044</ref> [[http://www.uniprot.org/uniprot/TLN1_CHICK TLN1_CHICK]] Probably involved in connections of major cytoskeletal structures to the plasma membrane. Talin is a high molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Gallus gallus]] | [[Category: Gallus gallus]] | ||
| - | [[Category: Barsukov, I L | + | [[Category: Barsukov, I L]] |
| - | [[Category: Critchley, D R | + | [[Category: Critchley, D R]] |
| - | [[Category: Emsley, J | + | [[Category: Emsley, J]] |
| - | [[Category: Gingras, A R | + | [[Category: Gingras, A R]] |
| - | [[Category: Papagrigoriou, E | + | [[Category: Papagrigoriou, E]] |
[[Category: Cell adhesion-protein binding complex]] | [[Category: Cell adhesion-protein binding complex]] | ||
[[Category: Talin]] | [[Category: Talin]] | ||
[[Category: Vinculin]] | [[Category: Vinculin]] | ||
Revision as of 08:03, 24 December 2014
Vinculin head (1-258) in complex with the talin vinculin binding site 3 (1945-1969)
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