1jhn
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1jhn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Canis_lupus_familiaris Canis lupus familiaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JHN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JHN FirstGlance]. <br> | <table><tr><td colspan='2'>[[1jhn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Canis_lupus_familiaris Canis lupus familiaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JHN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JHN FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jhn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jhn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jhn RCSB], [http://www.ebi.ac.uk/pdbsum/1jhn PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jhn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jhn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jhn RCSB], [http://www.ebi.ac.uk/pdbsum/1jhn PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CALX_CANFA CALX_CANFA]] Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse (By similarity). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Canis lupus familiaris]] | [[Category: Canis lupus familiaris]] | ||
| - | [[Category: Bergeron, J M | + | [[Category: Bergeron, J M]] |
| - | [[Category: Borisova, S | + | [[Category: Borisova, S]] |
| - | [[Category: Cygler, M | + | [[Category: Cygler, M]] |
| - | [[Category: Hahn, M | + | [[Category: Hahn, M]] |
| - | [[Category: Li, Y | + | [[Category: Li, Y]] |
| - | [[Category: Schrag, J D | + | [[Category: Schrag, J D]] |
| - | [[Category: Thomas, D Y | + | [[Category: Thomas, D Y]] |
[[Category: Beta sandwich]] | [[Category: Beta sandwich]] | ||
[[Category: Chaperone]] | [[Category: Chaperone]] | ||
[[Category: Jelly-roll]] | [[Category: Jelly-roll]] | ||
Revision as of 08:04, 24 December 2014
Crystal Structure of the Lumenal Domain of Calnexin
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