3uat
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3uat]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UAT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3UAT FirstGlance]. <br> | <table><tr><td colspan='2'>[[3uat]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UAT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3UAT FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr> | + | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Dlg1, Dlgh1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Dlg1, Dlgh1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3uat FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uat OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3uat RCSB], [http://www.ebi.ac.uk/pdbsum/3uat PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3uat FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uat OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3uat RCSB], [http://www.ebi.ac.uk/pdbsum/3uat PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/DLG1_RAT DLG1_RAT]] Essential multidomain scaffolding protein required for normal development (By similarity). Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells. Regulates the excitability of cardiac myocytes by modulating the functional expression of Kv4 channels. Functional regulator of Kv1.5 channel (By similarity). May play a role in adherens junction assembly, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation.<ref>PMID:14960569</ref> <ref>PMID:15044483</ref> <ref>PMID:15504326</ref> <ref>PMID:19213956</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Guanylate kinase domains of the MAGUK family scaffold proteins as specific phospho-protein-binding modules.,Zhu J, Shang Y, Xia C, Wang W, Wen W, Zhang M EMBO J. 2011 Nov 25. doi: 10.1038/emboj.2011.428. PMID:22117215<ref>PMID:22117215</ref> | Guanylate kinase domains of the MAGUK family scaffold proteins as specific phospho-protein-binding modules.,Zhu J, Shang Y, Xia C, Wang W, Wen W, Zhang M EMBO J. 2011 Nov 25. doi: 10.1038/emboj.2011.428. PMID:22117215<ref>PMID:22117215</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
| - | [[Category: Shang, Y | + | [[Category: Shang, Y]] |
| - | [[Category: Wen, W | + | [[Category: Wen, W]] |
| - | [[Category: Zhang, M | + | [[Category: Zhang, M]] |
| - | [[Category: Zhu, J | + | [[Category: Zhu, J]] |
[[Category: Dlg gk domain]] | [[Category: Dlg gk domain]] | ||
[[Category: Peptide binding protein]] | [[Category: Peptide binding protein]] | ||
[[Category: Phosphor-lgn]] | [[Category: Phosphor-lgn]] | ||
[[Category: Phosphor-peptide binding module]] | [[Category: Phosphor-peptide binding module]] | ||
Revision as of 08:11, 24 December 2014
Guanylate Kinase Domains of the MAGUK Family Scaffold Proteins as Specific Phospho-Protein Binding Modules
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