1w3z

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[[Image:1w3z.gif|left|200px]]<br /><applet load="1w3z" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1w3z.gif|left|200px]]
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caption="1w3z, resolution 3.2&Aring;" />
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'''SEMET DERIVATIVE OF BBCRASP-1 FROM BORRELIA BURGDORFERI'''<br />
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{{Structure
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|PDB= 1w3z |SIZE=350|CAPTION= <scene name='initialview01'>1w3z</scene>, resolution 3.2&Aring;
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|SITE=
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|LIGAND=
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|ACTIVITY=
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|GENE=
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}}
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'''SEMET DERIVATIVE OF BBCRASP-1 FROM BORRELIA BURGDORFERI'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1W3Z is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Borrelia_burgdorferi Borrelia burgdorferi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W3Z OCA].
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1W3Z is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Borrelia_burgdorferi Borrelia burgdorferi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W3Z OCA].
==Reference==
==Reference==
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A novel fold for the factor H-binding protein BbCRASP-1 of Borrelia burgdorferi., Cordes FS, Roversi P, Kraiczy P, Simon MM, Brade V, Jahraus O, Wallis R, Skerka C, Zipfel PF, Wallich R, Lea SM, Nat Struct Mol Biol. 2005 Mar;12(3):276-7. Epub 2005 Feb 13. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15711564 15711564]
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A novel fold for the factor H-binding protein BbCRASP-1 of Borrelia burgdorferi., Cordes FS, Roversi P, Kraiczy P, Simon MM, Brade V, Jahraus O, Wallis R, Skerka C, Zipfel PF, Wallich R, Lea SM, Nat Struct Mol Biol. 2005 Mar;12(3):276-7. Epub 2005 Feb 13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15711564 15711564]
[[Category: Borrelia burgdorferi]]
[[Category: Borrelia burgdorferi]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: tick]]
[[Category: tick]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:40:13 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:51:50 2008''

Revision as of 12:51, 20 March 2008

Image:1w3z.gif


PDB ID 1w3z

Drag the structure with the mouse to rotate
, resolution 3.2Å
Coordinates: save as pdb, mmCIF, xml



SEMET DERIVATIVE OF BBCRASP-1 FROM BORRELIA BURGDORFERI


Overview

Borrelia burgdorferi, a spirochete transmitted to human hosts during feeding of infected Ixodes ticks, is the causative agent of Lyme disease. Serum-resistant B. burgdorferi strains cause a chronic, multisystemic form of the disease and bind complement factor H (FH) and FH-like protein 1 (FHL-1) on the spirochete surface. Here we report the atomic structure for the key FHL-1- and FH-binding protein BbCRASP-1 and reveal a homodimer that presents a novel target for drug design.

About this Structure

1W3Z is a Single protein structure of sequence from Borrelia burgdorferi. Full crystallographic information is available from OCA.

Reference

A novel fold for the factor H-binding protein BbCRASP-1 of Borrelia burgdorferi., Cordes FS, Roversi P, Kraiczy P, Simon MM, Brade V, Jahraus O, Wallis R, Skerka C, Zipfel PF, Wallich R, Lea SM, Nat Struct Mol Biol. 2005 Mar;12(3):276-7. Epub 2005 Feb 13. PMID:15711564

Page seeded by OCA on Thu Mar 20 14:51:50 2008

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