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1n7t
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1n7t]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N7T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1N7T FirstGlance]. <br> | <table><tr><td colspan='2'>[[1n7t]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N7T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1N7T FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">erbin ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">erbin ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1n7t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n7t OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1n7t RCSB], [http://www.ebi.ac.uk/pdbsum/1n7t PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1n7t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n7t OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1n7t RCSB], [http://www.ebi.ac.uk/pdbsum/1n7t PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/LAP2_HUMAN LAP2_HUMAN]] Acts as an adapter for the receptor ERBB2, in epithelia. By binding the unphosphorylated 'Tyr-1248' of receptor ERBB2, it may contribute to stabilize this unphosphorylated state.<ref>PMID:10878805</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Koehler, M F.T | + | [[Category: Koehler, M F.T]] |
| - | [[Category: Lasky, L A | + | [[Category: Lasky, L A]] |
| - | [[Category: Pisabarro, M T | + | [[Category: Pisabarro, M T]] |
| - | [[Category: Sidhu, S S | + | [[Category: Sidhu, S S]] |
| - | [[Category: Skelton, N J | + | [[Category: Skelton, N J]] |
| - | [[Category: Wong, W L | + | [[Category: Wong, W L]] |
| - | [[Category: Yeh, S | + | [[Category: Yeh, S]] |
| - | [[Category: Yin, J P | + | [[Category: Yin, J P]] |
| - | [[Category: Zobel, K | + | [[Category: Zobel, K]] |
[[Category: C-terminal peptide complex]] | [[Category: C-terminal peptide complex]] | ||
[[Category: High affnity ligand]] | [[Category: High affnity ligand]] | ||
[[Category: Pdz domain]] | [[Category: Pdz domain]] | ||
[[Category: Signaling protein]] | [[Category: Signaling protein]] | ||
Revision as of 08:36, 24 December 2014
ERBIN PDZ domain bound to a phage-derived peptide
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