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1lqq
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1lqq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Leiurus_quinquestriatus_quinquestriatus Leiurus quinquestriatus quinquestriatus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LQQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1LQQ FirstGlance]. <br> | <table><tr><td colspan='2'>[[1lqq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Leiurus_quinquestriatus_quinquestriatus Leiurus quinquestriatus quinquestriatus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LQQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1LQQ FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1lqq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lqq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1lqq RCSB], [http://www.ebi.ac.uk/pdbsum/1lqq PDBsum]</span></td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1lqq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lqq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1lqq RCSB], [http://www.ebi.ac.uk/pdbsum/1lqq PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/SCX3_LEIQU SCX3_LEIQU]] Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission. This contractive toxin is highly toxic both to mammals and insects. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Leiurus quinquestriatus quinquestriatus]] | [[Category: Leiurus quinquestriatus quinquestriatus]] | ||
| - | [[Category: Landon, C | + | [[Category: Landon, C]] |
| - | [[Category: Ptak, M | + | [[Category: Ptak, M]] |
| - | [[Category: Sodano, P | + | [[Category: Sodano, P]] |
| - | [[Category: Vovelle, F | + | [[Category: Vovelle, F]] |
[[Category: Csalpha-beta motif]] | [[Category: Csalpha-beta motif]] | ||
[[Category: Lqqiii]] | [[Category: Lqqiii]] | ||
Revision as of 08:51, 24 December 2014
ANTI-MAMMAL AND ANTI-INSECT LQQIII SCORPION TOXIN, NMR, 15 STRUCTURES
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