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1mrl
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1mrl]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterococcus_faecium Enterococcus faecium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MRL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MRL FirstGlance]. <br> | <table><tr><td colspan='2'>[[1mrl]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterococcus_faecium Enterococcus faecium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MRL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MRL FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DOL:5-(2-DIETHYLAMINO-ETHANESULFONYL)-21-HYDROXY-10-ISOPROPYL-11,19-DIMETHYL-9,26-DIOXA-3,15,28-TRIAZA-TRICYCLO[23.2.1.00,255]OCTACOSA-1(27),12,17,19,25(28)-PENTAENE-2,8,14,23-TETRAONE'>DOL</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DOL:5-(2-DIETHYLAMINO-ETHANESULFONYL)-21-HYDROXY-10-ISOPROPYL-11,19-DIMETHYL-9,26-DIOXA-3,15,28-TRIAZA-TRICYCLO[23.2.1.00,255]OCTACOSA-1(27),12,17,19,25(28)-PENTAENE-2,8,14,23-TETRAONE'>DOL</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1mr7|1mr7]], [[1mr9|1mr9]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1mr7|1mr7]], [[1mr9|1mr9]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1mrl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mrl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1mrl RCSB], [http://www.ebi.ac.uk/pdbsum/1mrl PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1mrl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mrl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1mrl RCSB], [http://www.ebi.ac.uk/pdbsum/1mrl PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/VATD_ENTFC VATD_ENTFC]] Inactivates the A compounds of streptogramin antibiotics by acetylation, thus providing resistance to these antibiotics. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Enterococcus faecium]] | [[Category: Enterococcus faecium]] | ||
| - | [[Category: Courvalin, P | + | [[Category: Courvalin, P]] |
| - | [[Category: Kehoe, L E | + | [[Category: Kehoe, L E]] |
| - | [[Category: Murray, I A | + | [[Category: Murray, I A]] |
| - | [[Category: Rafferty, J B | + | [[Category: Rafferty, J B]] |
| - | [[Category: Snidwongse, J | + | [[Category: Snidwongse, J]] |
[[Category: Left-handed parallel beta-helix domain]] | [[Category: Left-handed parallel beta-helix domain]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 08:51, 24 December 2014
Crystal structure of streptogramin A acetyltransferase with dalfopristin
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