1x0o
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1x0o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X0O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1X0O FirstGlance]. <br> | <table><tr><td colspan='2'>[[1x0o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X0O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1X0O FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1x0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x0o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1x0o RCSB], [http://www.ebi.ac.uk/pdbsum/1x0o PDBsum]</span></td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1x0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x0o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1x0o RCSB], [http://www.ebi.ac.uk/pdbsum/1x0o PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ARNT_HUMAN ARNT_HUMAN]] Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Card, P B | + | [[Category: Card, P B]] |
| - | [[Category: Erbel, P J | + | [[Category: Erbel, P J]] |
| - | [[Category: Gardner, K H | + | [[Category: Gardner, K H]] |
[[Category: Arnt]] | [[Category: Arnt]] | ||
[[Category: Aryl hydrocarbon receptor nuclear translocator]] | [[Category: Aryl hydrocarbon receptor nuclear translocator]] | ||
Revision as of 09:03, 24 December 2014
human ARNT C-terminal PAS domain
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