4nni

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'''Unreleased structure'''
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==Structural basis for targeting the ribosomal protein S1 of Mycobacterium tuberculosis by pyrazinamide==
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<StructureSection load='4nni' size='340' side='right' caption='[[4nni]], [[Resolution|resolution]] 2.64&Aring;' scene=''>
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The entry 4nni is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4nni]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NNI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NNI FirstGlance]. <br>
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Authors: Yang, J., Liu, Y., Cai, Q., Lin, D.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=VGL:PYRAZINE-2-CARBOXYLIC+ACID'>VGL</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4nng|4nng]], [[4nnh|4nnh]], [[4nnk|4nnk]]</td></tr>
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Description: The Structure Basis: a Novel Target RpsA From Mycobacterium Tuberculosis Recognition of Pyrazinoic Acid for Inhibiting Trans-translation
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nni FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nni OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4nni RCSB], [http://www.ebi.ac.uk/pdbsum/4nni PDBsum]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/RS1_MYCTU RS1_MYCTU]] Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity).
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__TOC__
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</StructureSection>
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[[Category: Cai, Q]]
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[[Category: Lin, D]]
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[[Category: Liu, Y]]
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[[Category: Yang, J]]
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[[Category: Beta barrel]]
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[[Category: Ribosomal protein]]

Revision as of 11:06, 24 December 2014

Structural basis for targeting the ribosomal protein S1 of Mycobacterium tuberculosis by pyrazinamide

4nni, resolution 2.64Å

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