4u1a
From Proteopedia
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| - | ''' | + | ==Crystal structure of human peroxisomal delta3,delta2, enoyl-CoA isomerase helix-10 deletion mutant (ISOB-ECI2)== |
| - | + | <StructureSection load='4u1a' size='340' side='right' caption='[[4u1a]], [[Resolution|resolution]] 2.85Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4u1a]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U1A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4U1A FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dodecenoyl-CoA_isomerase Dodecenoyl-CoA isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.3.8 5.3.3.8] </span></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4u1a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u1a OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4u1a RCSB], [http://www.ebi.ac.uk/pdbsum/4u1a PDBsum]</span></td></tr> | |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ECI2_HUMAN ECI2_HUMAN]] Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. Has a preference for 3-trans substrates (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Dodecenoyl-CoA isomerase]] | ||
| + | [[Category: Koski, M K]] | ||
| + | [[Category: Onwukwe, G U]] | ||
| + | [[Category: Wierenga, R K]] | ||
| + | [[Category: Beta-oxidation]] | ||
| + | [[Category: Crotonase]] | ||
| + | [[Category: Isomerase]] | ||
| + | [[Category: Peci]] | ||
Revision as of 11:13, 24 December 2014
Crystal structure of human peroxisomal delta3,delta2, enoyl-CoA isomerase helix-10 deletion mutant (ISOB-ECI2)
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