4wpc

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'''Unreleased structure'''
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==Crystal structure of Rgd1p F-BAR domain in complex with inositol phosphate==
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<StructureSection load='4wpc' size='340' side='right' caption='[[4wpc]], [[Resolution|resolution]] 3.34&Aring;' scene=''>
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The entry 4wpc is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4wpc]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WPC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WPC FirstGlance]. <br>
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Authors: Moravcevic, K., Lemmon, M.A.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=I6P:INOSITOL+1,2,3,4,5,6-HEXAKISPHOSPHATE'>I6P</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wpc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wpc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wpc RCSB], [http://www.ebi.ac.uk/pdbsum/4wpc PDBsum]</span></td></tr>
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Description: Crystal structure of Rgd1p F-BAR domain in complex with inositol phosphate
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/RGD1_YEAST RGD1_YEAST]] GTPase activating protein of RHO3 and RHO4. Acts in concert with MID2 in cell integrity, which is functionally linked to the PKC pathway. Involved in various stress responses. Required at low pH for activation of the PKC pathway. Important during mating response.<ref>PMID:10526184</ref> <ref>PMID:10590461</ref> <ref>PMID:11779787</ref> <ref>PMID:15922872</ref> <ref>PMID:16087742</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Lemmon, M A]]
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[[Category: Moravcevic, K]]
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[[Category: F-bar domain]]
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[[Category: Phospholipid binding]]
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[[Category: Protein binding]]

Revision as of 11:16, 24 December 2014

Crystal structure of Rgd1p F-BAR domain in complex with inositol phosphate

4wpc, resolution 3.34Å

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